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C Abl/ABL1 Rabbit Polyclonal Antibody (Biotin)

CAT: 0013-GTR18566025Size: 100 µgDry Ice: NoHazardous: No
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CAT#:0013-GTR18566025Size:100 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Anti-c Abl/ABL1 Antibody. Tested in WB applications. This antibody reacts with Human, Rat.
Product Name Alternative
Tyrosine-protein kinase ABL1; 2.7.10.2; Abelson murine leukemia viral oncogene homolog 1; Abelson tyrosine-protein kinase 1; Proto-oncogene c-Abl; p150; ABL1; ABL, JTK7
UniProt
P00519
Reactivity
Human, Rat
Cross Reactivity
No cross-reactivity with other proteins
Immunogen
A synthetic peptide corresponding to a sequence at the C-terminus of human c Abl, different from the related mouse sequence by one amino acid.
Target
Tyrosine-protein kinase ABL1
Clonality
Polyclonal
Conjugation
Biotin
Field of Research
Cancer Biology, Cell Biology, Epigenetics & Chromatin, Protein Biochemistry, Signal Transduction
Purification
Immunogen affinity purified.
Dilution
Western blot, Optimal dilutions should be determined by end users. Immunohistochemistry (Paraffin-embedded Section), Optimal dilutions should be determined by end users. ELISA, Optimal dilutions should be determined by end users.
Form
Liquid
Molecular Weight
122873 Da
Storage Conditions
At -20°C for one year from date of receipt. Avoid repeated freezing and thawing.
Notes
For research use only.
Host or Source
Rabbit
Preservative
Each vial contains 50% glycerol, 0.9% NaCl, 0.2% Na2HPO4, 0.02% NaN3.
Isotype
Rabbit IgG

UniProtKB · P00519

Tyrosine-protein kinase ABL1

ABL1_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
P00519
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
ABL1
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
—
EC number
2.7.10.2
Processing
—
Secondary accessions
A3KFJ3, Q13869, Q13870, Q16133, Q17R61, Q45F09
Protein keywords

Technical term

3D-structureProteomics identificationReference proteome

PTM

AcetylationLipoproteinMyristatePhosphoproteinUbl conjugation

Coding sequence diversity

Alternative splicingChromosomal rearrangement

Biological process

ApoptosisAutophagyCell adhesionDNA damageDNA repairEndocytosis

Ligand

ATP-bindingMagnesiumManganeseMetal-bindingNucleotide-binding

Cellular component

CytoplasmCytoskeletonMembraneMitochondrionNucleus

Disease

Disease variantProto-oncogene

Molecular function

DNA-bindingKinaseTransferaseTyrosine-protein kinase

Domain

SH2 domainSH3 domain

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