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Chk2/CHEK2 Rabbit Polyclonal Antibody (APC)

CAT: 0013-GTR18564631Size: 100 µgDry Ice: NoHazardous: No
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CAT#:0013-GTR18564631Size:100 µg
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Description
Chk2/CHEK2 Rabbit Polyclonal Antibody (APC)
Product Name Alternative
Serine/threonine-protein kinase Chk2; 2.7.11.1; CHK2 checkpoint homolog; Cds1 homolog; Hucds1; hCds1; Checkpoint kinase 2; CHEK2; CDS1, CHK2, RAD53
UniProt
O96017
Reactivity
Human, Mouse, Rat
Cross Reactivity
No cross-reactivity with other proteins
Immunogen
A synthetic peptide corresponding to a sequence at the C-terminus of human Chk2, different from the related mouse sequence by four amino acids.
Target
Serine/threonine-protein kinase Chk2
Clonality
Polyclonal
Conjugation
APC
Field of Research
Cancer Biology, Cell Biology, Epigenetics & Chromatin, Molecular Biology, Protein Biochemistry
Purification
Immunogen affinity purified.
Dilution
Optimal dilutions should be determined by end users.
Form
Liquid
Molecular Weight
60915 Da
Storage Conditions
At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.
Notes
For research use only.
Applications Notes
Recommended applications are based on the parent unconjugated antibody. Customers may select suitable applications according to their experimental needs.
Host or Source
Rabbit
Preservative
Each vial contains 50% glycerol, 0.9% NaCl, 0.2% Na2HPO4, 0.02% NaN3.
Isotype
Rabbit IgG

UniProtKB · O96017

Serine/threonine-protein kinase Chk2

CHK2_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
O96017
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
CHEK2
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
—
EC number
2.7.11.1
Processing
—
Secondary accessions
A8K3Y9, B7ZBF3, B7ZBF4, B7ZBF5, Q6QA03, Q6QA04, Q6QA05, Q6QA06, Q6QA07, Q6QA08, Q6QA10, Q6QA11, Q6QA12, Q6QA13, Q9HBS5, Q9HCQ8, Q9UGF0, Q9UGF1
Protein keywords

Technical term

3D-structureProteomics identificationReference proteome

Coding sequence diversity

Alternative splicing

Biological process

ApoptosisCell cycleCell divisionDNA damageDNA repairHost-virus interactionMitosisTranscriptionTranscription regulation

Ligand

ATP-bindingMagnesiumMetal-bindingNucleotide-binding

Disease

Disease variantLi-Fraumeni syndromeTumor suppressor

Molecular function

KinaseSerine/threonine-protein kinaseTransferase

Cellular component

Nucleus

PTM

PhosphoproteinUbl conjugation

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