OSBPL7-IN-1
CAT:
804-HY-143200-06
Size:
10 mg
Price:
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- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No

OSBPL7-IN-1
- CAS Number: 1269826-44-9
- UNSPSC Description: OSBPL7-IN-1 is an orally active oxysterol binding protein like 7 (OSBPL7) inhibitor. OSBPL7-IN-1 promotes an increase of ABCA1 at the plasma membrane without affecting mRNA expression[1].
- Target Antigen: Apolipoprotein; Oxysterol-binding Protein-related Protein (ORP)
- Type: Reference compound
- Related Pathways: Metabolic Enzyme/Protease
- Applications: Metabolism-protein/nucleotide metabolism
- Field of Research: Metabolic Disease
- Assay Protocol: https://www.medchemexpress.com/osbpl7-in-1.html
- Solubility: DMSO : 125 mg/mL (ultrasonic;warming;heat to 60°C)
- Smiles: FC(F)(F)COC1=C(C2=CC(Cl)=C(C=C2)Cl)C=C(C=N1)C(N[C@H]3[C@@H](CCCC3)O)=O
- Molecular Weight: 463.28
- References & Citations: [1]Matthew B Wright, et al. Compounds targeting OSBPL7 increase ABCA1-dependent cholesterol efflux preserving kidney function in two models of kidney disease. Nat Commun. 2021 Aug 2;12(1):4662.
- Shipping Conditions: Blue Ice
- Clinical Information: No Development Reported