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Notch1 Rabbit Polyclonal Antibody (HRP)

CAT: 0013-GTR18560639Size: 100 µgDry Ice: NoHazardous: No
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CAT#:0013-GTR18560639Size:100 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Anti-Notch1 Antibody. Tested in WB applications. This antibody reacts with Human, Mouse.
Product Name Alternative
Neurogenic locus notch homolog protein 1; Notch 1; hN1; Translocation-associated notch protein TAN-1; Notch 1 extracellular truncation; NEXT; Notch 1 intracellular domain; NICD; NOTCH1; TAN1
UniProt
P46531
Reactivity
Human, Mouse
Cross Reactivity
No cross-reactivity with other proteins.
Immunogen
A synthetic peptide corresponding to a sequence in the middle region of human Notch1, identical to the related mouse and rat sequences.
Target
Neurogenic locus notch homolog protein 1
Clonality
Polyclonal
Conjugation
HRP
Field of Research
Cardiovascular Research, Cell Biology, Epigenetics & Chromatin, Neuroscience, Stem Cell & Developmental Biology
Purification
Immunogen affinity purified.
Form
Liquid
Molecular Weight
272505 Da
Storage Conditions
At -20°C for one year from date of receipt. Avoid repeated freezing and thawing.
Notes
For research use only.
Host or Source
Rabbit
Preservative
Each vial contains 50% glycerol, 0.9% NaCl, 0.2% Na2HPO4.
Isotype
Rabbit IgG

UniProtKB · P46531

Neurogenic locus notch homolog protein 1

NOTC1_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
P46531
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
NOTCH1
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
Notch 1, hN1
EC number
—
Processing
Precursor
Secondary accessions
Q59ED8, Q5SXM3
Protein keywords

Technical term

3D-structureDirect protein sequencingProteomics identificationReference proteome

Molecular function

ActivatorDevelopmental proteinReceptor

Biological process

AngiogenesisDifferentiationNotch signaling pathwayTranscriptionTranscription regulation

Domain

ANK repeatEGF-like domainRepeatSignalTransmembraneTransmembrane helix

Ligand

CalciumMetal-binding

Cellular component

Cell membraneEndosomeMembraneNucleus

Disease

Disease variant

PTM

Disulfide bondGlycoproteinHydroxylationIsopeptide bondPhosphoproteinUbl conjugation

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