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GGDPS-IN-1

CAT: 0804-HY-163334Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-163334Size:1 Each
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
GGDPS-IN-1 (Compound 37) is a geranylgeranyl diphosphate synthase (GGDPS) inhibitor with an IC50 of 49.4 nM. GGDPS-IN-1 disrupts protein geranylgeranylation in myeloma cells[1].
UNSPSC
12352005
Target
Ras
Type
Reference compound
Related Pathways
GPCR/G Protein; MAPK/ERK Pathway
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/ggdps-in-1.html
Solubility
10 mM in DMSO
Smiles
O=P(O)(C(CC1=CN(N=N1)CC/C=C(CC/C=C(C)/C)\C)(N)P(O)(O)=O)O
Molecular Formula
C15H28N4O6P2
Molecular Weight
422.35
References & Citations
[1]Gehrke NR, et al. α-Amino bisphosphonate triazoles serve as GGDPS inhibitors. Bioorg Med Chem Lett. 2024 Feb 17:129659.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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