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METTL3 Rabbit Polyclonal Antibody (Biotin)

CAT: 0013-GTR18550721Size: 100 µgDry Ice: NoHazardous: No
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CAT#:0013-GTR18550721Size:100 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Anti-METTL3 Antibody. Tested in ELISA, Flow Cytometry, IF, IHC, ICC, WB applications. This antibody reacts with Human.
Product Name Alternative
IME4; M6A; methyltransferase like 3; METTL3; MT A70; MTA70; Spo8
UniProt
Q86U44
Reactivity
Human
Cross Reactivity
No cross-reactivity with other proteins.
Immunogen
A synthetic peptide corresponding to a sequence at the C-terminus of human METTL3, which shares 100% and 95.3% amino acid (aa) sequence identity with mouse and rat METTL3, respectively.
Target
N
Clonality
Polyclonal
Conjugation
Biotin
Field of Research
Epigenetics & Chromatin, Molecular Biology, Signal Transduction
Purification
Immunogen affinity purified.
Dilution
Western blot, Optimal dilutions should be determined by end users. Immunohistochemistry (Paraffin-embedded Section), Optimal dilutions should be determined by end users. ELISA, Optimal dilutions should be determined by end users.
Form
Liquid
Storage Conditions
At -20°C for one year from date of receipt. Avoid repeated freezing and thawing.
Notes
For research use only.
Host or Source
Rabbit
Preservative
Each vial contains 50% glycerol, 0.9% NaCl, 0.2% Na2HPO4, 0.02% NaN3.
Isotype
Rabbit IgG

UniProtKB · Q86U44

N(6)-adenosine-methyltransferase catalytic subunit METTL3

MTA70_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
Q86U44
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
METTL3
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
—
EC number
2.1.1.348
Processing
—
Secondary accessions
O14736, Q86V05, Q9HB32
Protein keywords

Technical term

3D-structureDirect protein sequencingProteomics identificationReference proteome

PTM

AcetylationIsopeptide bondPhosphoproteinUbl conjugation

Coding sequence diversity

Alternative splicing

Biological process

Biological rhythmsDifferentiationDNA damageImmunityInnate immunityOogenesisSpermatogenesis

Cellular component

CytoplasmNucleus

Molecular function

MethyltransferaseRNA-bindingTransferase

Ligand

S-adenosyl-L-methionine

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