Phenanthrene

• Description :

  Phenanthrene is an orally active polycyclic aromatic hydrocarbon (PAH) that induces inflammation, oxidative stress, and apoptosis. Additionally, phenanthrene is commonly used to detect or assess PAH pollution in the environment[1][2][3][4].

• UNSPSC :

  12352005

• Hazard Statement :

  H302, H410

• Target :

  Apoptosis

• Type :

  Reference compound

• Related Pathways :

  Apoptosis

• Applications :

  COVID-19-immunoregulation

• Field of Research :

  Inflammation/Immunology; Cancer

• Assay Protocol :

  https://www.medchemexpress.com/phenanthrene.html

• Purity :

  99.82

• Solubility :

  DMSO : 200 mg/mL (ultrasonic)

• Smiles :

  C12=CC=CC=C1C=CC3=CC=CC=C23

• Molecular Formula :

  C14H10

• Molecular Weight :

  178.23

• Precautions :

  H302, H410

• References & Citations :

  [1]Sun K, et al. Subcellular distribution and biotransformation of phenanthrene in pakchoi after inoculation with endophytic Pseudomonas sp. as probed using HRMS coupled with isotope-labeling. Environ Pollut. 2018 Jun;237:858-867.|[2]Dupuy J, et al. Effect and localization of phenanthrene in maize roots. Chemosphere. 2016 Apr;149:130-6.|[3]Ma H, et al. Effects of phenanthrene on oxidative stress and inflammation in lung and liver of female rats. Environ Toxicol. 2020 Jan;35 (1) :37-46.|[4]Hong X, et al. Phenanthrene-Induced Apoptosis and Its Underlying Mechanism. Environ Sci Technol. 2017 Dec 19;51 (24) :14397-14405.

• Shipping Conditions :

  Room Temperature

• Storage Conditions :

  Store at room temperature 3 years

• Scientific Category :

  Reference compound1

• Clinical Information :

  Phase 1

• CAS Number :

  [85-01-8]