MMP2-IN-2

• UNSPSC Description:

  MMP2-IN-2 (compound 42) is a potent and selective MMP-2 (matrix metalloproteinases) inhibitor, with an IC50 of 4.2 μM. MMP2-IN-2 also shows inhibitory activity against MMP-13, MMP-9 and MMP-8, with IC50 values of 12, 23.3, and 25 μM, respectively[1].

• Target Antigen:

  MMP

• Type:

  Reference compound

• Related Pathways:

  Metabolic Enzyme/Protease

• Applications:

  Cancer-Kinase/protease

• Field of Research:

  Cancer

• Assay Protocol:

  https://www.medchemexpress.com/mmp2-in-2.html

• Solubility:

  DMSO : 7.14 mg/mL (ultrasonic;warming;heat to 60°C)

• Smiles:

  O=[N+](C1=CC=C(C2=NC3=CC=C([N+]([O-])=O)C=C3N2)C=C1)[O-]

• Molecular Weight:

  284.23

• References & Citations:

  [1]Laghezza A, et al. Virtual screening identification and chemical optimization of substituted 2-arylbenzimidazoles as new non-zinc-binding MMP-2 inhibitors. Bioorg Med Chem. 2020 Feb 1;28(3):115257.

• Shipping Conditions:

  Room Temperature

• Clinical Information:

  No Development Reported

• CAS Number:

  1772-39-0