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Methyl oleanonate

CAT: 0804-HY-N7624-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-N7624-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Methyl oleanonate is a natural triterpene PPARγ agonist isolated from the species of Pistacia lentiscus var. Chia[1]. Methyl oleanonate is a modified oleanolic acid derivative with anti-cancer effects[2].
CAS Number
1721-58-0
Product Name Alternative
3-Oxoolean-12-en-28-oic acid methyl ester
UNSPSC
12352211
Target
PPAR
Type
Natural Products
Related Pathways
Cell Cycle/DNA Damage; Metabolic Enzyme/Protease; Vitamin D Related/Nuclear Receptor
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/methyl-oleanonate.html
Purity
99.81
Solubility
DMSO : 2.5 mg/mL (ultrasonic; warming; heat to 60°C)
Smiles
CC1(C)C(CC[C@]2(C)[C@@]3([H])CC=C4[C@]5([H])CC(C)(C)CC[C@@](C(OC)=O)5CC[C@](C)4[C@@](C)3CC[C@@]12[H])=O
Molecular Formula
C31H48O3
Molecular Weight
468.71
References & Citations
[1]Rasmus K Petersen, et al. Pharmacophore-driven identification of PPARγ agonists from natural sources. J Comput Aided Mol Des. 2011 Feb;25 (2) :107-16.|[2]Barbara Bednarczyk-Cwynar, et al. Anticancer effect of A-ring or/and C-ring modified oleanolic acid derivatives on KB, MCF-7 and HeLa cell lines. Org Biomol Chem. 2012 Mar 21;10 (11) :2201-5
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Natural Products
Clinical Information
No Development Reported
Isoform
PPARγ