Protein Inhibitor Of Activated STAT 1 (PIAS1) Polyclonal Antibody (Human), Biotinylated

• Catalog number
  PAB736Hu01-200ul-Biotin
• Price
  Please ask
• Size
  200ul

• Description
  A Rabbit polyclonal antibody against Human Protein Inhibitor Of Activated STAT 1 (PIAS1). This antibody is labeled with Biotin.
• Specifications
  Host: Rabbit; Species Reactivity: Human; Clonality: polyclonal; Tested applications: WB, IHC; Concentration: 500ug/ml; Isotype: IgG; Conjugation: Biotin
• Additional_information
  Sequence of the immunogen: PIAS1 (Glu409~Pro645); Buffer composition: PBS, pH7.4, containing 0.02% NaN3, 50% glycerol.
• Storage_and_shipping
  Upon receipt, store at -20°C or -80°C. Prepare working aliqotes prior to storage to avoid repeated freeze-thaw cycles.
• Notes
  Research Use Only.
• Properties
  If you buy Antibodies supplied by Cloud Clone Corp they should be stored frozen at - 24°C for long term storage and for short term at + 5°C. Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.
• Additional description
  Tissue, pathway, proteinase, peptidase, protease ,acrosin, lipoprotein, activator, caspase, trypsin, papain, esterase inhibitors are proteins or receptor ligands or receptor antagonists that bind to an enzyme receptor and decreases its activity. Since blocking an enzyme's activity can kill a pathogen or correct a metabolic imbalance, many drugs are enzyme inhibitors. Not all receptor antagonist that bind to enzymes are inhibitors; enzyme activator ligands or agonists bind to enzymes and increase their enzymatic activity, while enzyme substrates bind and are converted to products in the normal catalytic cycle of the enzyme. STAT proteins are phosphorylated by receptor related kinases and for homo or hetero dimers. JAK-STAT pathways are signaling to the nucleus of the cell.
• Group
  Polyclonals and antibodies
• About
  Polyclonals can be used for Western blot, immunohistochemistry on frozen slices or parrafin fixed tissues. The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera.
• French translation
  anticorps

• Gene target
  Protein   Inhibitor   Activated   STAT   PIAS1   Biotinylated  
• Gene symbol
  STAT6, SOAT1, PIAS1
• Short name
  Protein Inhibitor Of Activated STAT 1 (PIAS1) Polyclonal Antibody ( ), Biotinylated
• Technique
  Polyclonal, Antibody, antibodies against human proteins, antibodies for, Polyclonal antibodies (pAbs) are mostly rabbit or goat antibodies that are secreted by different B cells, whereas monoclonal antibodies come from a single N cell lineage. Pabs are a collection of immunoglobulin molecules that react against a specific antigen, each identifying a different epitope.
• Species
  Human, Humans
• Alternative name
  Protein suppressor on Activated Signal transducer and activation on transcription 1 (PIAS1) polyclonal (antibody to-) (H. sapiens), Biotinylated
• Alternative technique
  polyclonals, antibodies

Gene info

• Identity
  HGNC:11368
• Gene
  STAT6
• Long gene name
  signal transducer and activator of transcription 6
• Synonyms gene name
  • signal transducer and activator of transcription 6, interleukin-4 induced
• Synonyms
  • D12S1644
  • IL-4-STAT
• GenBank acession
  • BC005823
  • BQ028928
• Locus
  12q13.3
• Discovery year
  1995-11-09
• Entrez gene record
  6778
• Pubmed identfication
  • 9605853
  • 8085155
• RefSeq identity
  • NM_003153
• Classification
  • SH2 domain containing
• VEGA ID
  OTTHUMG00000171194
• Locus Specific Databases
  • LRG_1369

Gene info

• Identity
  HGNC:11177
• Gene
  SOAT1
• Long gene name
  sterol O-acyltransferase 1
• Synonyms gene
  • SOAT
  • STAT
• Synonyms gene name
  • sterol O-acyltransferase (acyl-Coenzyme A: cholesterol acyltransferase) 1
• Synonyms
  • ACAT
  • ACAT1
• Synonyms name
  • acyl-Coenzyme A: cholesterol acyltransferase
• GenBank acession
  • L21934
• Locus
  1q25.2
• Discovery year
  1998-11-04
• Entrez gene record
  6646
• Pubmed identfication
  • 8407899
• RefSeq identity
  • NM_003101
• VEGA ID
  OTTHUMG00000035253

Gene info

• Identity
  HGNC:2752
• Gene
  PIAS1
• Long gene name
  protein inhibitor of activated STAT 1
• Synonyms gene
  • DDXBP1
• Synonyms gene name
  • DEAD/H (Asp-Glu-Ala-Asp/His) box binding protein 1
• Synonyms
  • GBP
  • GU/RH-II
  • ZMIZ3
• Synonyms name
  • zinc finger, MIZ-type containing 3
• GenBank acession
  • AF077951
• Locus
  15q23
• Discovery year
  1998-11-06
• Entrez gene record
  8554
• Pubmed identfication
  • 9724754
  • 9177271
  • 19526197
• Classification
  • Zinc fingers MIZ-type
• VEGA ID
  OTTHUMG00000172645

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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