Mouse PIAS1 (Protein Inhibitor Of Activated STAT 1) CLIA Kit

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Description

Tissue, pathway, proteinase, peptidase, protease ,acrosin, lipoprotein, activator, caspase, trypsin, papain, esterase inhibitors are proteins or receptor ligands or receptor antagonists that bind to an enzyme receptor and decreases its activity. Since blocking an enzyme's activity can kill a pathogen or correct a metabolic imbalance, many drugs are enzyme inhibitors. Not all receptor antagonist that bind to enzymes are inhibitors; enzyme activator ligands or agonists bind to enzymes and increase their enzymatic activity, while enzyme substrates bind and are converted to products in the normal catalytic cycle of the enzyme. STAT proteins are phosphorylated by receptor related kinases and for homo or hetero dimers. JAK-STAT pathways are signaling to the nucleus of the cell.
Test

Mouse or mice from the Mus musculus species are used for production of mouse monoclonal antibodies or mabs and as research model for humans in your lab. Mouse are mature after 40 days for females and 55 days for males. The female mice are pregnant only 20 days and can give birth to 10 litters of 6-8 mice a year. Transgenic, knock-out, congenic and inbread strains are known for C57BL/6, A/J, BALB/c, SCID while the CD-1 is outbred as strain.
Latin name

Mus musculus

Gene target

PIAS1 Protein Inhibitor Activated STAT CLIA Kit
Gene symbol

STAT6, SOAT1, PIAS1
Short name

Mouse PIAS1 (Protein Inhibitor Of Activated STAT 1) CLIA Kit
Technique

Mouse, mouses
Host

mouse
Species

Mouse, Mouses
Alternative name

Mouse PIAS1 (Protein suppressor on Activated Signal transducer and activation on transcription 1) CLIA reagent
Alternative technique

murine, kits
Alternative to gene target

v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog, C-Kit and CD117 and PBT and SCFR, KIT and IDBG-18980 and ENSG00000157404 and 3815, transferase activity, Extracellular, Kit and IDBG-172083 and ENSMUSG00000005672 and 16590, KIT and IDBG-642326 and ENSBTAG00000002699 and 280832

Identity

HGNC:11368
Gene

STAT6
Long gene name

signal transducer and activator of transcription 6
Synonyms gene name
- signal transducer and activator of transcription 6, interleukin-4 induced
Synonyms
- D12S1644
- IL-4-STAT
GenBank acession
- BC005823
- BQ028928
Locus

12q13.3
Discovery year

1995-11-09
Entrez gene record

6778
Pubmed identfication
- 9605853
- 8085155
RefSeq identity
- NM_003153
Classification
- SH2 domain containing
VEGA ID

OTTHUMG00000171194
Locus Specific Databases
- LRG_1369

Identity

HGNC:11177
Gene

SOAT1
Long gene name

sterol O-acyltransferase 1
Synonyms gene
- SOAT
- STAT
Synonyms gene name
- sterol O-acyltransferase (acyl-Coenzyme A: cholesterol acyltransferase) 1
Synonyms
- ACAT
- ACAT1
Synonyms name
- acyl-Coenzyme A: cholesterol acyltransferase
GenBank acession
- L21934
Locus

1q25.2
Discovery year

1998-11-04
Entrez gene record

6646
Pubmed identfication
- 8407899
RefSeq identity
- NM_003101
VEGA ID

OTTHUMG00000035253