TERT Antibody

• Catalog number
  bs-1411R
• Price
  Please ask
• Size
  0.1ml

• Long name
  TERT Primary Polyclonal Antibody
• Also known as
  TERT PAb
• Category
  Primary Antibodies
• Conjugation
  Unconjugated
• Target Antigen
  TERT
• Specificity
  This is a highly specific antibody against TERT.
• Modification s
  None
• Modification site s
  Unmodified antibody
• Clonality
  Polyclonal antibody
• Clone number
  Polyclonal antibody
• Concentration
  1ug per 1ul
• Immunogen range
  560-600/1132
• Subcellular location
  Cytoplasm, Nucleus
• Source
  This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human TERT
• Gene ID number
  7015
• Swiss Prot
  O14746
• Tested Applications
  IHC-P, IF(IHC-P), IF(ICC)
• Recommended dilutions
  IHC-P(1:100-500), IF(IHC-P)(1:50-200), IF(ICC)(1:50-200)
• Cross reactivity
  Human, Mouse, Rat
• Cross reactive species details
  Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.
• Background of the target antigen
  Telomerase is a ribonucleoprotein enzyme essential for the replication of chromosome termini in most eukaryotes. Active in progenitor and cancer cells. Inactive, or very low activity, in normal somatic cells. Catalytic component of the teleromerase holoenzyme complex whose main activity is the elongation of telomeres by acting as a reverse transcriptase that adds simple sequence repeats to chromosome ends by copying a template sequence within the RNA component of the enzyme. Catalyzes the RNA-dependent extension of 3'-chromosomal termini with the 6-nucleotide telomeric repeat unit, 5'-TTAGGG-3'. The catalytic cycle involves primer binding, primer extension and release of product once the template boundary has been reached or nascent product translocation followed by further extension. More active on substrates containing 2 or 3 telomeric repeats. Telomerase activity is regulated by a number of factors including telomerase complex-associated proteins, chaperones and polypeptide modifiers. Modulates Wnt signaling. Plays important roles in aging and antiapoptosis.
• Purification method
  This antibody was purified via Protein A.
• Storage conditions
  Keep the antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store at -20°C for up to 1 year.
• Synonym names
  TP2; TRT; CMM9; EST2; TCS1; hTRT; DKCA2; DKCB4; hEST2; PFBMFT1; Telomerase reverse transcriptase; Telomerase catalytic subunit; Telomerase-associated protein 2; TERT
• Properties
  If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• French translation
  anticorps

• Gene target
  TERT  
• Gene symbol
  TERT
• Short name
  Anti-TERT
• Technique
  Antibody, antibodies against human proteins, antibodies for
• Host
  Rabbit (Oryctolagus cuniculus)
• Isotype
  Immunoglobulin G (IgG)
• Alternative name
  TERT Polyclonal Antibody
• Alternative technique
  antibodies
• Alternative to gene target
  telomerase reverse transcriptase, CMM9 and DKCA2 and DKCB4 and EST2 and hEST2 and hTRT and PFBMFT1 and TCS1 and TP2 and TRT, TERT and IDBG-10998 and ENSG00000164362 and 7015, telomeric RNA binding, nuclei, Tert and IDBG-165912 and ENSMUSG00000021611 and 21752, BT.60929 and IDBG-632169 and ENSBTAG00000012567 and 518884

Gene info

• Identity
  HGNC:11730
• Gene
  TERT
• Long gene name
  telomerase reverse transcriptase
• Synonyms
  • TRT
  • TP2
  • TCS1
  • hEST2
  • EST2
• GenBank acession
  • AF015950
• Locus
  5p15.33
• Discovery year
  1998-01-21
• Pubmed identfication
  • 9252327
• VEGA ID
  OTTHUMG00000090357
• Locus Specific Databases
  • LRG_343

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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