SLC5A8 Antibody

• Catalog number
  bs-6106R
• Price
  Please ask
• Size
  0.1ml

• Long name
  SLC5A8 Primary Polyclonal Antibody
• Also known as
  SLC5A8 PAb
• Category
  Primary Antibodies
• Conjugation
  Unconjugated
• Target Antigen
  SLC5A8
• Specificity
  This is a highly specific antibody against SLC5A8.
• Modification s
  None
• Modification site s
  Unmodified antibody
• Clonality
  Polyclonal antibody
• Clone number
  Polyclonal antibody
• Concentration
  1ug per 1ul
• Immunogen range
  301-336/610
• Subcellular location
  Extracellular
• Source
  This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human SLC5A8
• Gene ID number
  160728
• Swiss Prot
  Q8N695
• Tested Applications
  WB, IHC-P, IF(IHC-P)
• Recommended dilutions
  WB(1:100-1000), IHC-P(1:100-500), IF(IHC-P)(1:50-200)
• Cross reactivity
  Human, Mouse, Rat
• Cross reactive species details
  Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.
• Background of the target antigen
  Acts as an electrogenic sodium (Na(+)) and chloride (Cl-)-dependent sodium-coupled solute transporter, including transport of monocarboxylates (short-chain fatty acids including L-lactate, D-lactate, pyruvate, acetate, propionate, valerate and butyrate), lactate, mocarboxylate drugs (nicotinate, benzoate, salicylate and 5-aminosalicylate) and ketone bodies (beta-D-hydroxybutyrate, acetoacetate and alpha-ketoisocaproate), with a Na(+):substrate stoichiometry of between 4:1 and 2:1. Catalyzes passive carrier mediated diffusion of iodide. Mediates iodide transport from the thyrocyte into the colloid lumen through the apical membrane. May be responsible for the absorption of D-lactate and monocarboxylate drugs from the intestinal tract. Acts as a tumor suppressor, suppressing colony formation in colon cancer, prostate cancer and glioma cell lines. May play a critical role in the entry of L-lactate and ketone bodies into neurons by a process driven by an electrochemical Na(+) gradient and hence contribute to the maintenance of the energy status and function of neurons.
• Purification method
  This antibody was purified via Protein A.
• Storage conditions
  Keep the antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store at -20°C for up to 1 year.
• Synonym names
  AIT; SMCT; SMCT1; Sodium-coupled monocarboxylate transporter 1; Apical iodide transporter; Electrogenic sodium monocarboxylate cotransporter; Sodium iodide-related cotransporter; Solute carrier family 5 member 8; SLC5A8
• Properties
  If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• French translation
  anticorps

• Gene target
  SLC5A8  
• Gene symbol
  SLC5A8
• Short name
  Anti-SLC5A8
• Technique
  Antibody, antibodies against human proteins, antibodies for
• Host
  Rabbit (Oryctolagus cuniculus)
• Isotype
  Immunoglobulin G (IgG)
• Alternative name
  SLC5A8 Polyclonal Antibody
• Alternative technique
  antibodies
• Alternative to gene target
  solute carrier family 5 (iodide transporter), member 8, SLC5A8 and IDBG-547244 and ENSG00000256870 and 160728, symporter activity, Plasma membranes, Slc5a8 and IDBG-183999 and ENSMUSG00000020062 and 216225, SMCT1 and IDBG-636931 and ENSBTAG00000011525 and 615734

Gene info

• Identity
  HGNC:19119
• Gene
  SLC5A8
• Long gene name
  solute carrier family 5 member 8
• Synonyms gene name
  • solute carrier family 5 (iodide transporter), member 8
  • solute carrier family 5 (sodium/monocarboxylate cotransporter), member 8
• Synonyms
  • AIT
• GenBank acession
  • AY081220
• Locus
  12q23.1-q23.2
• Discovery year
  2003-05-12
• Entrez gene record
  160728
• Pubmed identfication
  • 12107270
  • 12829793
• RefSeq identity
  • NM_145913
• Classification
  • Solute carriers
• VEGA ID
  OTTHUMG00000170499

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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