SIGLEC10 Antibody, ALEXA FLUOR 488
#
-
Catalog numberbs-2706R-A488
-
Price:
-
Size100ul
-
-
Long nameSIGLEC10 Polyclonal Antibody, ALEXA FLUOR 488 Conjugated
-
Also known asAnti-SIGLEC10 PAb ALEXA FLUOR 488
-
CategoryConjugated Primary Antibodies
-
Conjugated withALEXA FLUOR® 488
-
Host OrganismRabbit (Oryctolagus cuniculus)
-
Target AntigenSIGLEC10
-
SpecificityThis is a highly specific antibody against SIGLEC10.
-
ModificationUnmodified
-
Modification SiteNone
-
ClonalityPolyclonal
-
ClonePolyclonal antibody
-
Concentration1ug per 1ul
-
Subcellular locationExtracellular
-
SourceThis antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human SIGLEC10
-
Tested applicationsFCM, IF(IHC-P)
-
Recommended dilutionsFCM(1:20-100), IF(IHC-P)(1:50-200)
-
CrossreactivityHuman, Mouse, Rat
-
Cross reactive species detailsDue to limited amount of testing and knowledge, not every possible cross-reactivity is known.
-
Background of the antigenSIGLEC10 is a putative adhesion molecule that mediates sialic-acid dependent binding to cells. It preferentially binds to alpha2,3- or 2,6-linked sialic acid. The sialic acid recognition site may be masked by cis interactions with sialic acids on the same cell surface. In the immune response, may act as an inhibitory receptor upon ligand induced tyrosine phosphorylation by recruiting cytoplasmic phosphatase(s) via their SH2 domain(s) that block signal transduction through dephosphorylation of signaling molecules. SIGLEC10 interacts with PTPN6/SHP-1 upon phosphorylation. The protein is expressed by peripheral blood leukocytes (eosinophils, monocytes and a natural killer cell subpopulation).
-
PurificationPurified by Protein A.
-
Storage conditionsStore this antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Keep refrigerated at 2 to 8 degrees Celcius for up to one year.
-
Excitation emission499nm/519nm
-
SynonymsPRO940; mSiglec G; Sialic acid binding Ig like lectin 10; Sialic acid binding Ig like lectin 10; sialic acid binding Ig like lectin 10 Ig like lectin 7; sialic acid binding Ig like lectin G; Sialic acid binding Immunoglobulin like lectin 10; SIGLEC 10; Siglec G; siglec like gene 2; Siglec like protein 2; Siglec like protein 2; Siglecg; SLG2.
-
PropertiesFor facs or microscopy Alexa 1 conjugate. Alexa Fluor 488 has the same range to that of fluorescein isothiocyanate (FITC), yet the Anti-SIGLEC10 has a very high photo stability. As a result of this photo stability, it has turned into an antibody for fluorescent microscopy and FACS FLOW cytometry. It is distinguished in the FL1 of a FACS-Calibur or FACScan. Also Alexa Fluor 488 is pH stable. If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies. ALEXA FLUOR they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
-
ConjugationAlexa Fluor
-
French translationanticorps
-
Gene target
-
Gene symbolSIGLEC10-AS1, SIGLEC10
-
Short nameAnti-SIGLEC10
-
TechniqueAntibody, antibodies against human proteins, antibodies for
-
IsotypeImmunoglobulin G (IgG)
-
LabelALEXA FLUOR 488
-
Alternative nameSIGLEC10 Polyclonal Antibody, ALEXA FLUOR 488
-
Alternative techniqueantibodies
-
Alternative to gene targetsialic acid binding Ig-like lectin 10, SIGLEC10 and IDBG-65888 and ENSG00000142512 and 89790, protein binding, Extracellular
-
Gene info
-
Identity
-
Gene
-
Long gene nameSIGLEC10 antisense RNA 1
-
Locus
-
Discovery year2020-03-20
-
Entrez gene record
-
RefSeq identity
-
Classification
- Antisense RNAs
Gene info
-
Identity
-
Gene
-
Long gene namesialic acid binding Ig like lectin 10
-
Synonyms gene name
- sialic acid binding Ig-like lectin 10
-
Synonyms
-
Synonyms name
-
GenBank acession
-
Locus
-
Discovery year2001-06-29
-
Entrez gene record
-
Pubmed identfication
-
RefSeq identity
-
Classification
- C2-set domain containing
- Sialic acid binding Ig like lectins
- V-set domain containing
-
VEGA ID
MeSH Data
-
Name
-
ConceptScope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
-
Tree numbers
- E05.196.401.143
- E05.301.300.096
- E05.478.566.320.200
- E05.601.262
- E05.601.470.320.200
-
Qualifiersethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data