SIGLEC10 Antibody, ALEXA FLUOR 647

• Catalog number
  bs-2706R-A647
• Price
  Please ask
• Size
  100ul

• Long name
  SIGLEC10 Polyclonal Antibody, ALEXA FLUOR 647 Conjugated
• Also known as
  Anti-SIGLEC10 PAb ALEXA FLUOR 647
• Category
  Conjugated Primary Antibodies
• Conjugated with
  ALEXA FLUOR® 647
• Host Organism
  Rabbit (Oryctolagus cuniculus)
• Target Antigen
  SIGLEC10
• Specificity
  This is a highly specific antibody against SIGLEC10.
• Modification
  Unmodified
• Modification Site
  None
• Clonality
  Polyclonal
• Clone
  Polyclonal antibody
• Concentration
  1ug per 1ul
• Subcellular location
  Extracellular
• Source
  This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human SIGLEC10
• Tested applications
  FCM, IF(IHC-P)
• Recommended dilutions
  FCM(1:20-100), IF(IHC-P)(1:50-200)
• Crossreactivity
  Human, Mouse, Rat
• Cross reactive species details
  Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.
• Background of the antigen
  SIGLEC10 is a putative adhesion molecule that mediates sialic-acid dependent binding to cells. It preferentially binds to alpha2,3- or 2,6-linked sialic acid. The sialic acid recognition site may be masked by cis interactions with sialic acids on the same cell surface. In the immune response, may act as an inhibitory receptor upon ligand induced tyrosine phosphorylation by recruiting cytoplasmic phosphatase(s) via their SH2 domain(s) that block signal transduction through dephosphorylation of signaling molecules. SIGLEC10 interacts with PTPN6/SHP-1 upon phosphorylation. The protein is expressed by peripheral blood leukocytes (eosinophils, monocytes and a natural killer cell subpopulation).
• Purification
  Purified by Protein A.
• Storage conditions
  Store this antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Keep refrigerated at 2 to 8 degrees Celcius for up to one year.
• Excitation emission
  650nm/665nm
• Synonyms
  PRO940; mSiglec G; Sialic acid binding Ig like lectin 10; Sialic acid binding Ig like lectin 10; sialic acid binding Ig like lectin 10 Ig like lectin 7; sialic acid binding Ig like lectin G; Sialic acid binding Immunoglobulin like lectin 10; SIGLEC 10; Siglec G; siglec like gene 2; Siglec like protein 2; Siglec like protein 2; Siglecg; SLG2.
• Properties
  For facs or microscopy Alexa 1 conjugate. Alexa Fluor 633 is a practical alternative to APC as well as Cy5. Bioss Primary Conjugated Antibodies. ALEXA FLUOR made this Alexa Fluor 633 conjugate that can be used in multi-color flow cytometry with instruments equipped with a second red laser or red diode. It is detected in the FL4 detector of the core's upgraded 2-laser FACScans. Like other Alexa Fluor dyes, the Anti-SIGLEC10 exhibits uncommon photo stability, making it an ideal choice for fluorescent microscopy. If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies. ALEXA FLUOR they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• Conjugation
  Alexa Fluor, ALEXA FLUOR 647
• French translation
  anticorps

• Gene target
  SIGLEC10  
• Gene symbol
  SIGLEC10-AS1, SIGLEC10
• Short name
  Anti-SIGLEC10
• Technique
  Antibody, antibodies against human proteins, antibodies for
• Isotype
  Immunoglobulin G (IgG)
• Label
  ALEXA FLUOR 647
• Alternative name
  SIGLEC10 Polyclonal Antibody, ALEXA FLUOR 647
• Alternative technique
  antibodies
• Alternative to gene target
  sialic acid binding Ig-like lectin 10, SIGLEC10 and IDBG-65888 and ENSG00000142512 and 89790, protein binding, Extracellular

Gene info

• Identity
  HGNC:40719
• Gene
  SIGLEC10-AS1
• Long gene name
  SIGLEC10 antisense RNA 1
• Locus
  19q13.41
• Discovery year
  2020-03-20
• Entrez gene record
  100129083
• RefSeq identity
  • NR_164124
• Classification
  • Antisense RNAs

Gene info

• Identity
  HGNC:15620
• Gene
  SIGLEC10
• Long gene name
  sialic acid binding Ig like lectin 10
• Synonyms gene name
  • sialic acid binding Ig-like lectin 10
• Synonyms
  • SIGLEC-10
  • SLG2
  • PRO940
  • MGC126774
• Synonyms name
  • sialic acid binding Ig-like lectin 10 Ig-like lectin 7
  • siglec-like gene 2
• GenBank acession
  • AF310233
• Locus
  19q13.41
• Discovery year
  2001-06-29
• Entrez gene record
  89790
• Pubmed identfication
  • 11284738
• RefSeq identity
  • NM_033130
• Classification
  • C2-set domain containing
  • Sialic acid binding Ig like lectins
  • V-set domain containing
• VEGA ID
  OTTHUMG00000165521

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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