RIZ1 2 200 aa GST tagged Human recombinant

RIZ1 2 200 aa GST tagged Human recombinant is available 2 times from Biovision labs

7672-100 | RIZ1 (2-200 aa) (GST-tagged), Human recombinantsize: 100 μg | 332.48 USD

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7672-50 | RIZ1 (2-200 aa) (GST-tagged), Human recombinantsize: 50 μg | 204.87 USD

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  • Target
    PRDM2
  • Background
    Retinoblastoma protein-interacting zinc finger protein 1 (RIZ1), also known as PRDM2, is a SAM-dependent histone methyltransferase that specifically methylates histone H3 on lysine 9. RIZ1 contains 8 zinc-finger motifs and 1 PR domain. The RIZ gene encodes two different proteins, RIZ1 and RIZ2. RIZ1 is a tumor suppressor that can arrest the cell cycle and induce apoptosis. RIZ2 however, is a proto-oncoprotein lacking the N-terminal PR domain containing the methyltransferase activity. When RIZ1 is silenced or mutated, the reduced methyltransferase activity can lead to inheritable changes in chromatin methylation and gene expression patterns.
  • Concentration
    N/A
  • Molecular weight
    49.5 kDa (2-200 aa + NT GST Tag)
  • Synonym
    RIZ1 (2-200 aa) (GST-tagged), Human recombinant
  • Other name
    KMT8; PRDM2; PR Domain Zinc Finger Protein 2; Retinoblastoma Protein-interacting Zinc Finger Protein
  • NCBI gene number
    7799
  • NCBI gene
    PRDM2
  • Gene source
    Human
  • NCBI number
    Q13029
  • Recombinant
    Yes
  • Source
    E. coli
  • Purification
    ≥95%
  • Tested applications
    SDS-PAGE, HPLC
  • Level of endotoxin
    N/A
  • Tested activity
    N/A
  • Biological activity
    N/A
  • Reesults
    N/A
  • Binding ability
    N/A
  • Unit
    N/A
  • Storage condition
    -80°C
  • Shipping under
    dry ice
  • Physical appearance
    Liquid
  • Physical properties
    50 mM Tris, pH 7.5, containing 150 mM sodium chloride and 20% glycerol.
  • How to reconstitute
    N/A
  • Aa sequence
    N/A
  • Before use
    Centrifuge the vial prior to opening.
  • Notes
    For Research Use Only! Not to be used in humans
  • Properties
    Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.
  • Additional source
    Recombinants or rec. proteins
  • Group
    recombinants
  • Gene target
  • Short name
    RIZ1 (2-200 aa) (GST-tagged) recombinant
  • Technique
    Recombinant
  • Species
    Human
  • Alternative name
    RIZ1 (2-200 aa) (GST-tagged), H. sapiens recombinant
  • Alternative technique
    rec
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