Human GRB2 (Growth Factor Receptor-Bound Protein 2) Recombinant Protein 6xHis-GST Tagged

• Catalog number
  MBS698056
• Price
  Please ask
• Size
  5x1 mg

• Products_type
  Recombinant Protein
• Products_short_name
  [GRB2 (Growth Factor Receptor-Bound Protein 2)]
• Products_name_syn
  [Growth Factor Receptor-Bound Protein 2; Abundant Src homology protein; ASH; Growth factor receptor bound protein 2]
• Other_names
  [growth factor receptor-bound protein 2 isoform 1; Growth factor receptor-bound protein 2; growth factor receptor-bound protein 2; growth factor receptor bound protein 2; Adapter protein GRB2; Protein Ash; SH2/SH3 adapter GRB2]
• Products_gene_name
  [GRB2]
• Other_gene_names
  [GRB2; GRB2; ASH; Grb3-3; MST084; NCKAP2; MSTP084; EGFRBP-GRB2; ASH]
• Purity
  >95%Purification: 6xHis-GST tags, Immobilized-metal affinity chromatography (IMAC)
• Form
  Frozen/Solution; Phosphate-Buffered Saline (PBS), pH 7.4. No preservatives added.
• Storage_stability
  For extended storage, conserve at -80 degree C. Repeated freezing and thawing is not recommended. Store working aliquots at 4 degree C for up to one week.
• Tested_application
  ELISA (EIA), Western Blot (WB), Antibody Production, Protein Array
• Conjugated
  The polyhistidine (6xHis) tag or Histidine Epitope Tag (HIS Tag, 6XHIS Tag with Histidine (abbreviated as His or H; encoded by the codons CAU and CAC) is an α-amino acid that is used in the biosynthesis of proteins. It is the most used tag for purification by Affinity Chromatography (IMAC). The pentadentate chelator is the best chelator in Immobilized Metal ion Affinity chromatography (IMAC) for the6xhis-tagged proteins.
• Description
  Aplha, transcription related growth factors and stimulating factors or repressing nuclear factors are complex subunits of proteins involved in cell differentiation. Complex subunit associated factors are involved in hybridoma growth, Eosinohils, eritroid proliferation and derived from promotor binding stimulating subunits on the DNA binding complex. NFKB 105 subunit for example is a polypetide gene enhancer of genes in B cells. The receptors are ligand binding factors of type 1, 2 or 3 and protein-molecules that receive chemical-signals from outside a cell. When such chemical-signals couple or bind to a receptor, they cause some form of cellular/tissue-response, e.g. a change in the electrical-activity of a cell. In this sense, am olfactory receptor is a protein-molecule that recognizes and responds to endogenous-chemical signals, chemokinesor cytokines e.g. an acetylcholine-receptor recognizes and responds to its endogenous-ligand, acetylcholine. However, sometimes in pharmacology, the term is also used to include other proteins that are drug-targets, such as enzymes, transporters and ion-channels.
• Properties
  Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.
• Source
  Recombinants or rec. proteins
• Group
  recombinants

• Gene target
  GRB2   Growth   Factor   Receptor-Bound   Protein   Protein   GST   Tagged  
• Gene symbol
  GRB2, MGST3
• Short name
  GRB2 (Growth Factor Receptor-Bound Protein 2) Recombinant Protein -GST Tagged
• Technique
  Recombinant, E. coli recombinant proteins are genetic recombinations in Escherichia coli, supplied as white sterile powder lyopillized. MyBioSource advises they will be reconstituted in a buffer soluion or culture medium for cell culture.
• Host
  E Coli
• Species
  Human, Humans
• Alternative name
  H. sapiens GRB2 (Growth Factor Receptor-Bound Protein 2) Rec. Protein 6xHis-GST Tagged
• Alternative technique
  rec

Gene info

• Identity
  HGNC:4566
• Gene
  GRB2
• Long gene name
  growth factor receptor bound protein 2
• Synonyms gene name
  • growth factor receptor-bound protein 2
• Synonyms
  • NCKAP2
• Locus
  17q25.1
• Discovery year
  1994-03-04
• Entrez gene record
  2885
• Pubmed identfication
  • 10051406
• RefSeq identity
  • NM_002086
• Classification
  • SH2 domain containing
• VEGA ID
  OTTHUMG00000134332

Gene info

• Identity
  HGNC:7064
• Gene
  MGST3
• Long gene name
  microsomal glutathione S-transferase 3
• Synonyms
  • GST-III
• Synonyms name
  • microsomal glutathione S-transferase III
  • microsomal GST-3
  • microsomal GST-III
• GenBank acession
  • AF026977
• Locus
  1q24.1
• Discovery year
  1997-10-16
• Entrez gene record
  4259
• Pubmed identfication
  • 9278457
• RefSeq identity
  • NM_004528
• Classification
  • Microsomal glutathione S-transferases
• VEGA ID
  OTTHUMG00000034627

MeSH Data

• Name
  Primary Cell Culture
• Concept
  Scope note: The initial culturing of cells derived directly from fresh TISSUES.
• Tree numbers
  • E01.370.225.500.223.500
  • E05.200.500.265.500
  • E05.242.223.500
  • E05.481.500.249.500
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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