RAR alpha Antibody, ALEXA FLUOR 555
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Catalog numberbs-0251R-A555
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Price:
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Size100ul
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Long nameRAR alpha Polyclonal Antibody, ALEXA FLUOR 555 Conjugated
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Also known asAnti-RAR alpha PAb ALEXA FLUOR 555
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CategoryConjugated Primary Antibodies
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Conjugated withALEXA FLUOR® 555
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Host OrganismRabbit (Oryctolagus cuniculus)
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Target AntigenRAR alpha
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SpecificityThis is a highly specific antibody against RAR alpha.
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ModificationUnmodified
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Modification SiteNone
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ClonalityPolyclonal
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ClonePolyclonal antibody
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Concentration1ug per 1ul
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Immunogen range410-462/462
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Subcellular locationCytoplasm, Nucleus
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SourceOVA conjugated synthetic peptide derived from mouse Retinoic acid Receptor Alpha
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Gene ID Number19401
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Swiss ProtP11416
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Tested applicationsIF(IHC-P)
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Recommended dilutionsIF(IHC-P)(1:50-200)
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CrossreactivityHuman, Mouse, Rat
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Cross reactive species detailsDue to limited amount of testing and knowledge, not every possible cross-reactivity is known.
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Background of the antigenReceptor for retinoic acid. Retinoic acid receptors bind as heterodimers to their target response elements in response to their ligands, all-trans or 9-cis retinoic acid, and regulate gene expression in various biological processes. The RXR/RAR heterodimers bind to the retinoic acid response elements (RARE) composed of tandem 5'-AGGTCA-3' sites known as DR1-DR5. In the absence of ligand, the RXR-RAR heterodimers associate with a multiprotein complex containing transcription corepressors that induce histone acetylation, chromatin condensation and transcriptional suppression. On ligand binding, the corepressors dissociate from the receptors and associate with the coactivators leading to transcriptional activation. Regulates expression of target genes in a ligand-dependent manner by recruiting chromatin complexes containing KMT2E/MLL5. Mediates retinoic acid-induced granulopoiesis. RARA plays an essential role in the regulation of retinoic acid-induced germ cell development during spermatogenesis. Has a role in the survival of early spermatocytes at the beginning prophase of meiosis. In Sertoli cells, may promote the survival and development of early meiotic prophase spermatocytes. In concert with RARG, required for skeletal growth, matrix homeostasis and growth plate function.
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PurificationPurified by Protein A.
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Storage conditionsStore this antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Keep refrigerated at 2 to 8 degrees Celcius for up to one year.
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Excitation emission553nm/568nm
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SynonymsRAR; Nr1b1; RARalpha1; Retinoic acid receptor alpha; RAR-alpha; Nuclear receptor subfamily 1 group B member 1; Rara
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PropertiesFor facs or microscopy Alexa 1 conjugate. Very high photo stable ALEXA conjugate. If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies. ALEXA FLUOR they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
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ConjugationAlexa Fluor, ALEXA FLUOR 555
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DescriptionThe Anti-RAR alpha is a α- or alpha protein sometimes glycoprotein present in blood.
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French translationanticorps
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Gene target
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Gene symbolRARA, PRAM1, RAB40B, RAB40A
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Short nameAnti-RAR alpha
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TechniqueAntibody, antibodies against human proteins, antibodies for
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IsotypeImmunoglobulin G (IgG)
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LabelALEXA FLUOR 555
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Alternative nameRAR alpha Polyclonal Antibody, ALEXA FLUOR 555
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Alternative techniqueantibodies
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Gene info
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Identity
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Gene
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Long gene nameretinoic acid receptor alpha
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Synonyms gene name
- retinoic acid receptor, alpha
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Synonyms
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GenBank acession
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Locus
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Discovery year1988-06-09
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Entrez gene record
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Pubmed identfication
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Classification
- Retinoic acid receptors
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VEGA ID
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Locus Specific Databases
Gene info
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Identity
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Gene
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Long gene namePML-RARA regulated adaptor molecule 1
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Synonyms
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GenBank acession
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Locus
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Discovery year2005-07-04
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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VEGA ID
Gene info
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Identity
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Gene
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Long gene nameRAB40B, member RAS oncogene family
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Synonyms
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GenBank acession
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Locus
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Discovery year2002-02-22
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Entrez gene record
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Pubmed identfication
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Classification
- RAB, member RAS oncogene GTPases
- MicroRNA protein coding host genes
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VEGA ID
Gene info
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Identity
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Gene
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Long gene nameRAB40A, member RAS oncogene family
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Synonyms
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GenBank acession
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Locus
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Discovery year2002-02-22
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Entrez gene record
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Pubmed identfication
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Classification
- RAB, member RAS oncogene GTPases
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VEGA ID
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Locus Specific Databases
MeSH Data
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Name
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ConceptScope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
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Tree numbers
- E05.196.401.143
- E05.301.300.096
- E05.478.566.320.200
- E05.601.262
- E05.601.470.320.200
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Qualifiersethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data