Integrin alpha 2bAntibody, ALEXA FLUOR 555
#
-
Catalog numberbs-2636R-A555
-
Price:
-
Size100ul
-
-
Long nameIntegrin alpha 2bPolyclonal Antibody, ALEXA FLUOR 555 Conjugated
-
Also known asAnti-Integrin alpha 2b/CD41 PAb ALEXA FLUOR 555
-
CategoryConjugated Primary Antibodies
-
Conjugated withALEXA FLUOR® 555
-
Host OrganismRabbit (Oryctolagus cuniculus)
-
Target AntigenIntegrin alpha 2b/CD41
-
SpecificityThis is a highly specific antibody against Integrin alpha 2b/CD41.
-
ModificationUnmodified
-
Modification SiteNone
-
ClonalityPolyclonal
-
ClonePolyclonal antibody
-
Concentration1ug per 1ul
-
Immunogen range370-420/1033
-
Subcellular locationExtracellular
-
SourceKLH conjugated synthetic peptide derived from mouse Integrin alpha 2b
-
Gene ID Number16399
-
Swiss ProtQ9QUM0
-
Tested applicationsIF(IHC-P)
-
Recommended dilutionsIF(IHC-P)(1:50-200)
-
CrossreactivityHuman, Mouse, Rat
-
Cross reactive species detailsDue to limited amount of testing and knowledge, not every possible cross-reactivity is known.
-
Background of the antigenIntegrin alpha-IIb/beta-3 is a receptor for fibronectin, fibrinogen, plasminogen, prothrombin, thrombospondin and vitronectin. It recognizes the sequence R-G-D in a wide array of ligands. It recognizes the sequence H-H-L-G-G-G-A-K-Q-A-G-D-V in fibrinogen gamma chain. Following activation integrin alpha-IIb/beta-3 brings about platelet/platelet interaction through binding of soluble fibrinogen. This step leads to rapid platelet aggregation which physically plugs ruptured endothelial cell surface.
-
PurificationPurified by Protein A.
-
Storage conditionsStore this antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Keep refrigerated at 2 to 8 degrees Celcius for up to one year.
-
Excitation emission553nm/568nm
-
SynonymsCD41; CD41B; GpIIb; AI172977; alphaIIb; Integrin alpha-IIb; GPalpha IIb; Platelet membrane glycoprotein IIb; Itga2b
-
PropertiesFor facs or microscopy Alexa 1 conjugate. Very high photo stable ALEXA conjugate.
-
ConjugationAlexa Fluor, ALEXA FLUOR 555
-
DescriptionThe Anti-Integrin alpha 2b/CD41 is a α- or alpha protein sometimes glycoprotein present in blood.
-
Gene target
-
Short nameAnti-Integrin alpha 2b/CD41
-
IsotypeImmunoglobulin G (IgG)
-
LabelALEXA FLUOR 555
-
Alternative nameIntegrin alpha 2bPolyclonal Antibody, ALEXA FLUOR 555
-
MeSH Data
-
Name
-
ConceptScope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
-
Tree numbers
- E05.196.401.143
- E05.301.300.096
- E05.478.566.320.200
- E05.601.262
- E05.601.470.320.200
-
Qualifiersethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data