Plakoglobin Antibody (gamma Catenin)
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Catalog number
R31599
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Price
Please ask
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Size
0.1mg
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Category
Antibody
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Concentration
0.5mg/ml if reconstituted with 0.2ml sterile DI water
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Form
Antigen affinity purified
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Conjugation
Unconjugated
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Clone
Polyclonal antibody
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Recognised antigen
Plakoglobin (gamma Catenin)
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Host animal
Rabbit (Oryctolagus cuniculus)
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Clonality
Polyclonal (rabbit origin)
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Species reactivity
Human (Homo sapiens), Mouse (Mus musculus), Rat ; Due to limited knowledge and inability to test the antibody against all known species, we cannot guarantee that no other cross reactivity can occur.
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Tested applications
WB, IHC-P, IHC-F, ICC
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Recommended dilutions
Western blot: 0.5-1ug/ml,IHC (Paraffin): 0.5-1ug/ml,IHC (Frozen): 0.5-1ug/ml,Immunocytochemistry: 0.5-1ug/ml
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Notes
The stated application concentrations are suggested starting amounts. Titration of the Plakoglobin antibody may be required due to differences in protocols and secondary/substrate sensitivity.
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Intented use
This gamma Catenin antibodyis to be used only for research purposes and not for diagnostics..
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Gene ID
3728
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Purity
Antigen affinity
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Description
Junction Plakoglobin (JUP), also known asgamma-catenin, is a protein that in humans is encoded by the JUP gene. It is a member of the catenin protein family and homologous tob-catenin, and it is mapped to 17q21.2. This gene encodes a major cytoplasmic protein that is the only known constituent common to submembranous plaques of both desmosomes and intermediate junctions. This protein forms distinct complexes with cadherins and desmosomal cadherins. Additionally, Plakoglobin may have distinct roles in Wnt signaling and cancer via differential effects on downstream target genes.
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Immunogen
Human partial recombinant protein (AA 556-745) was used as the immunogen for this Plakoglobin antibody.
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Storage
After reconstitution, the Plakoglobin antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20 deg. Celcius or lower. Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity. Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized. Avoid repeated freezing and thawing.
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Properties
If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
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French translation
anticorps
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Gene target
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Gene symbol
JUP
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Short name
Anti-Plakoglobin (gamma Catenin)
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Technique
Antibody, antibodies against human proteins, antibodies for
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Isotype
Rabbit IgG
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Alternative name
Antibodies to Plakoglobin (gamma Catenin)
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Alternative technique
antibodies
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Gene info
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Identity
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Gene
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Long gene name
junction plakoglobin
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Synonyms gene
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Synonyms gene name
- catenin (cadherin-associated protein), gamma 80kDa
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Synonyms
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Synonyms name
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GenBank acession
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Locus
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Discovery year
1991-03-04
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Beta catenins
- Armadillo repeat containing
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VEGA ID
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Locus Specific Databases
MeSH Data
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Name
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Concept
Scope note:
Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
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Tree numbers
- E05.196.401.143
- E05.301.300.096
- E05.478.566.320.200
- E05.601.262
- E05.601.470.320.200
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Qualifiers
ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data
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