gamma Catenin Antibody

• Catalog number
  R30282
• Price
  Please ask
• Size
  0.1mg

• Category
  Antibody
• Concentration
  0.5mg/ml if reconstituted with 0.2ml sterile DI water
• Form
  Antigen affinity purified
• Conjugation
  Unconjugated
• Clone
  Polyclonal antibody
• Recognised antigen
  gamma Catenin
• Host animal
  Rabbit (Oryctolagus cuniculus)
• Clonality
  Polyclonal (rabbit origin)
• Species reactivity
  Human (Homo sapiens), Mouse (Mus musculus), Rat ; Due to limited knowledge and inability to test the antibody against all known species, we cannot guarantee that no other cross reactivity can occur.
• Tested applications
  WB, IHC-P
• Recommended dilutions
  Western blot: 0.5-1ug/ml,IHC (Paraffin): 0.5-1ug/ml
• Notes
  The stated application concentrations are suggested starting amounts. Titration of the gamma Catenin antibody may be required due to differences in protocols and secondary/substrate sensitivity.
• Intented use
  This gamma Catenin antibodyis to be used only for research purposes and not for diagnostics..
• Uniprot
  P14923
• Purity
  Antigen affinity
• Description
  Gamma Catenin, also known as junction Plakoglobin (JUP) or plakoglobin (PKGB). Gamma Catenin is a major cytoplasmic protein which is the only known constituent common to submembranous plaques of both desmosomes and intermediate junctions. Cateninbeta and gamma Catenin, vertebrate homologs of Drosophila armadillo, function in cell adhesion and the Wnt signaling pathway. It may have a distinct role in Wnt signaling and cancer via differential effects on downstream target genes.
• Immunogen
  An amino acid sequence from the N-terminus of human gamma Catenin (EQPIKVTEWQQTYTY) was used as the immunogen for this gamma Catenin antibody (100% homologous in human, mouse and rat).
• Storage
  After reconstitution, the gamma Catenin antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20 deg. Celcius or lower. Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity. Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized. Avoid repeated freezing and thawing.
• Properties
  If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• French translation
  anticorps

• Gene target
  gamma   Catenin  
• Gene symbol
  JUP
• Short name
  Anti-gamma Catenin
• Technique
  Antibody, antibodies against human proteins, antibodies for
• Isotype
  Rabbit IgG
• Alternative name
  Antibodies to gamma Catenin
• Alternative technique
  antibodies

Gene info

• Identity
  HGNC:6207
• Gene
  JUP
• Long gene name
  junction plakoglobin
• Synonyms gene
  • CTNNG
• Synonyms gene name
  • catenin (cadherin-associated protein), gamma 80kDa
• Synonyms
  • DP3
  • PDGB
  • PKGB
  • DPIII
  • PG
• Synonyms name
  • desmosomal protein 3
• GenBank acession
  • AF233882
• Locus
  17q21.2
• Discovery year
  1991-03-04
• Entrez gene record
  3728
• Pubmed identfication
  • 1889810
  • 7604000
• RefSeq identity
  • NM_001352773
• Classification
  • Beta catenins
  • Armadillo repeat containing
• VEGA ID
  OTTHUMG00000133494
• Locus Specific Databases
  • Gene Connection for the Heart; Naxos disease database
  • Global Variome shared LOVD
  • LRG_401

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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