PD-173074

Chemical available in other sizes

Please inquire size and price
Stock availability

In Stock
Cas number

219580-11-7
Chemical s molecular weight

523.67
Chemical s main applications

PD 173074 is a selective FGFR1 and FGFR3 inhibitor. PD 173074 is a compound induced a dose-dependent reduce in cell viability and an increase in apoptosis, accompanied by a decrease in extracellular signal-related kinase phosphorylation.
Chemical s category

Aromatics, Heterocycles, Inhibitors, Nucleotides, Bases & Related Reagents, Pharmaceuticals, Intermediates & Fine Chemicals
Other name

N-[2-[[4-(Diethylamino)butyl]amino]-6-(3,5-dimethoxyphenyl)pyrido[2,3-d]pyrimidin-7-yl]-N'-(1,1-dimethylethyl)urea; PD 173074; PF-01367255
Chemical s formula

C28H41N7O3
Physical properties

Pale Yellow to Yellow Solid
Melting temperature

90-93°C
Boiling temperature

No Data Available
Chemical s soluble in

Chloroform (Slightly), Methanol (Slightly)
Stability conditions

No Data Available
Storage

Refrigerator
Chemical s specifications

Identity

HGNC:3358
Gene

ENPP3
Long gene name

ectonucleotide pyrophosphatase/phosphodiesterase 3
Synonyms gene
- PDNP3
Synonyms
- PD-IBETA
- gp130RB13-6
- B10
- CD203c
GenBank acession
- AF005632
Locus

6q23.2
Discovery year

1995-08-10
Entrez gene record

5169
Pubmed identfication
- 9344668
Classification
- Ectonucleotide pyrophosphatase/phosphodiesterase family
- CD molecules
VEGA ID

OTTHUMG00000016292

Identity

HGNC:18731
Gene

PDCD1LG2
Long gene name

programmed cell death 1 ligand 2
Synonyms
- PD-L2
- Btdc
- PDL2
- bA574F11.2
- CD273
- B7-DC
Synonyms name
- B7 dendritic cell molecule
GenBank acession
- AF344424
Locus

9p24.1
Discovery year

2003-11-14
Entrez gene record

80380
Pubmed identfication
- 11224527
RefSeq identity
- NM_025239
Classification
- B7 family
- CD molecules
- Immunoglobulin like domain containing
- Receptor ligands
VEGA ID

OTTHUMG00000019504