PD 173074

• Catalog number
  1675-100
• Price
  Please ask
• Size
  100 mg

• Alternative_name
  N-[2-[[4-(Diethylamino)butyl]amino]-6-(3,5-dimethoxyphenyl)pyrido[2,3-d]pyrimidin-7-yl]-N’-(1,1-dimethylethyl)urea
• Description
  A potent and selective FGFR1 tyrosine kinase inhibitor (IC₅₀ = 21.5 nM). Blocking of the FGFR signaling pathway by PD 173074 leads to self-renewal of stem cells via ERK1/2 activation. Treatment of FGF2-expressing human multipotent adipose-derived stem cells with PD173074 decreases dramatically their clonogenicity and differentiation potential.
• CAS Number
  219580-11-7
• Structure Available
  Yes
• Salt Form
  No
• Molecular Formula
  C₂₈H₄₁N₇O₃
• Molecular Weight
  523.67
• Cell Permeable
  Yes
• Purity
  ≥98% by TLC
• Solubilities
  DMSO (10 mg/ml)
• Handling
  Protect from air and light
• Tag Line
  A FGFR1 kinase inhibitor
• Storage Condition
  -20°C
• Shipping Condition
  gel pack
• Shelf Life
  24 months
• MDL Number
  MFCD11045982
• PubChem CID
  1401
• PubChem CID Link
• SMILES
  CCN(CC)CCCCNC1=NC2=NC(=C(C=C2C=N1)C3=CC(=CC(=C3)OC)OC)NC(=O)NC(C)(C)C
• InChi
  InChI=1S/C28H41N7O3/c1-8-35(9-2)13-11-10-12-29-26-30-18-20-16-23(19-14-21(37-6)17-22(15-19)38-7)25(31-24(20)32-26)33-27(36)34-28(3,4)5/h14-18H,8-13H2,1-7H3,(H3,29,30,31,32,33,34,36)
• InChi Key
  DXCUKNQANPLTEJ-UHFFFAOYSA-N
• Data Sheet Link
• MSDS Available
  Yes

• Gene target
  173074  
• Short name
  PD 173074
• Alternative name
  PD 173074

Product images

Similar products