NMDAR2B (Tyr1336) Antibody

• Catalog number
  bs-5381R
• Price
  Please ask
• Size
  0.1ml

• Long name
  NMDAR2B (Tyr1336) Primary Polyclonal Antibody
• Also known as
  NMDAR2B (Tyr1336) PAb
• Category
  Primary Antibodies
• Conjugation
  Unconjugated
• Target Antigen
  NMDAR2B Tyr1336
• Specificity
  This is a highly specific antibody against NMDAR2B Tyr1336. This phosphorylation site is homologous to that of Tyr1336 in Mouse and Rat.
• Modification s
  Phosphorylation
• Modification site s
  Tyr1336
• Clonality
  Polyclonal antibody
• Clone number
  Polyclonal antibody
• Concentration
  1ug per 1ul
• Immunogen range
  1310-1360/1484
• Subcellular location
  Cytoplasm
• Source
  KLH conjugated synthetic phosphopeptide derived from human NMDAR2B around the phosphorylation site of Tyr1336
• Gene ID number
  2904
• Swiss Prot
  Q13224
• Tested Applications
  WB, FCM, IHC-P, IF(IHC-P)
• Recommended dilutions
  WB(1:100-1000), FCM(1:20-100), IHC-P(1:100-500), IF(IHC-P)(1:50-200)
• Cross reactivity
  Human, Mouse, Rat
• Cross reactive species details
  Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.
• Background of the target antigen
  NMDA receptor subtype of glutamate-gated ion channels with high calcium permeability and voltage-dependent sensitivity to magnesium. Mediated by glycine. In concert with DAPK1 at extrasynaptic sites, acts as a central mediator for stroke damage. Its phosphorylation at Ser-1303 by DAPK1 enhances synaptic NMDA receptor channel activity inducing injurious Ca2+ influx through them, resulting in an irreversible neuronal death (By similarity).
• Purification method
  This antibody was purified via Protein A.
• Storage conditions
  Keep the antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store at -20°C for up to 1 year.
• Synonym names
  MRD6; NR2B; hNR3; GluN2B; NMDAR2B; Glutamate receptor ionotropic, NMDA 2B; Glutamate [NMDA] receptor subunit epsilon-2; N-methyl D-aspartate receptor subtype 2B; N-methyl-D-aspartate receptor subunit 3; NR3; GRIN2B
• Properties
  If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• French translation
  anticorps

• Gene target
  NMDAR2B   Tyr1336  
• Gene symbol
  GRIN2B
• Short name
  Anti-NMDAR2B Tyr1336
• Technique
  Antibody, antibodies against human proteins, antibodies for
• Host
  Rabbit (Oryctolagus cuniculus)
• Isotype
  Immunoglobulin G (IgG)
• Alternative name
  NMDAR2B (Tyr1336) Polyclonal Antibody
• Alternative technique
  antibodies

Gene info

• Identity
  HGNC:4586
• Gene
  GRIN2B
• Long gene name
  glutamate ionotropic receptor NMDA type subunit 2B
• Synonyms gene
  • NMDAR2B
• Synonyms gene name
  • glutamate receptor, ionotropic, N-methyl D-aspartate 2B
• Synonyms
  • GluN2B
• Locus
  12p13.1
• Discovery year
  1992-09-18
• Entrez gene record
  2904
• Pubmed identfication
  • 1350383
• Classification
  • Glutamate ionotropic receptor NMDA type subunits
• VEGA ID
  OTTHUMG00000137373

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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