NEDD4L (Ser342) Antibody

• Catalog number
  bs-3299R
• Price
  Please ask
• Size
  0.1ml

• Long name
  NEDD4L (Ser342) Primary Polyclonal Antibody
• Also known as
  NEDD4L (Ser342) PAb
• Category
  Primary Antibodies
• Conjugation
  Unconjugated
• Target Antigen
  NEDD4L Ser342
• Specificity
  This is a highly specific antibody against NEDD4L Ser342.
• Modification s
  Phosphorylation
• Modification site s
  Ser342
• Clonality
  Polyclonal antibody
• Clone number
  Polyclonal antibody
• Concentration
  1ug per 1ul
• Source
  KLH conjugated synthetic phosphopeptide derived from human NEDD4L around the phosphorylation site of Ser342
• Gene ID number
  23327
• Tested Applications
  WB, IHC-P, IF(IHC-P)
• Recommended dilutions
  WB(1:100-1000), IHC-P(1:100-500), IF(IHC-P)(1:50-200)
• Cross reactivity
  Human, Mouse, Rat
• Cross reactive species details
  Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.
• Background of the target antigen
  E3 ubiquitin-protein ligase accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates. This protein inhibits TGF-beta signaling by triggering SMAD2 and TGFR1 ubiquitination and proteasome-dependent degradation. Furthermore, it promotes ubiquitination and internalization of various plasma membrane channels such as ENaC, Nav1.2, Nav1.3, Nav1.5, Nav1.7, Nav1.8, Kv1.3, EAAT1 or CLC5, and promotes the ubiquitination and degradation of SGK.
• Purification method
  This antibody was purified via Protein A.
• Storage conditions
  Keep the antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store at -20°C for up to 1 year.
• Synonym names
  E3 ubiquitin protein ligase NEDD4 like protein; E3 ubiquitin-protein ligase NEDD4-like; E3 ubiquitin-protein ligase NEDD4-like protein; KIAA0439; NED4L_HUMAN; NEDD4 2; NEDD4 2c; NEDD4-2; NEDD4-2a; NEDD4.2; NEDD4b; NEDD4L; NEDD4La; NEDD4Lb; NEDD4Lc; NEDD4Ld; NEDD4Le; NEDD4Lf; NEDD4Lg; NEDD4Lh; NEDL3; Neural precursor cell expressed developmentally down regulated 4 like E3 ubiquitin protein ligase; Neural precursor cell expressed, developmentally down regulated 4 like; RSP5; Ubiquitin protein ligase Rsp5.
• Properties
  If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• French translation
  anticorps

• Gene target
  NEDD4L   Ser342  
• Gene symbol
  NEDD4L
• Short name
  Anti-NEDD4L Ser342
• Technique
  Antibody, antibodies against human proteins, antibodies for
• Host
  Rabbit (Oryctolagus cuniculus)
• Isotype
  Immunoglobulin G (IgG)
• Alternative name
  NEDD4L (Ser342) Polyclonal Antibody
• Alternative technique
  antibodies
• Alternative to gene target
  neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase, hNEDD4-2 and NEDD4-2 and NEDD4.2 and RSP5, NEDD4L and IDBG-3835 and ENSG00000049759 and 23327, ion channel binding, nuclei, Nedd4l and IDBG-154290 and ENSMUSG00000024589 and 83814, NEDD4L and IDBG-644828 and ENSBTAG00000005412 and 510003

Gene info

• Identity
  HGNC:7728
• Gene
  NEDD4L
• Long gene name
  NEDD4 like E3 ubiquitin protein ligase
• Synonyms gene name
  • neural precursor cell expressed, developmentally down-regulated 4-like
  • neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase
• Synonyms
  • KIAA0439
  • RSP5
  • NEDD4-2
• GenBank acession
  • AF210730
• Locus
  18q21.31
• Discovery year
  2000-03-14
• Entrez gene record
  23327
• Pubmed identfication
  • 10594025
  • 11244092
  • 18322022
• Classification
  • HECT domain containing
  • C2 domain containing
• VEGA ID
  OTTHUMG00000179875

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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