MOUSE ANTI HUMAN GLUCOCORTICOID RECEPTOR:FITC
-
Catalog numberMBS210980
-
PricePlease ask
-
Size0.1 mg
-
-
Products_typeAntibody
-
Products_short_name[GLUCOCORTICOID RECEPTOR]
-
Other_names[glucocorticoid receptor isoform alpha; Glucocorticoid receptor; glucocorticoid receptor; glucocorticoid nuclear receptor variant 1; nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor); Nuclear receptor subfamily 3 group C member 1]
-
Other_gene_names[NR3C1; NR3C1; GR; GCR; GRL; GCCR; GCRST; GRL; GR]
-
ClonalityMonoclonal
-
Clone[5E4]
-
FormFITC Purified IgG conjugated to Fluorescein Isothiocyanate Isomer 1 (FITC) - liquid
-
ConcentrationIgG concentration 0.1 mg/ml
-
Storage_stabilityStore at 4 degree C or at -20 degree C if preferred. Storage in frost-free freezers is not recommended. This product should be stored undiluted. This product is photosensitive and should be protected from light. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use. Shelf Life: 18 months from date of despatch.
-
Tested_applicationFlow cytometry (FC/FACS)*
-
DescriptionThis antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided. Antibody against the Hu protein or peptide or recombinant supplied in 1 volumes. Ask for quote if you need bulk. The receptors are ligand binding factors of type 1, 2 or 3 and protein-molecules that receive chemical-signals from outside a cell. When such chemical-signals couple or bind to a receptor, they cause some form of cellular/tissue-response, e.g. a change in the electrical-activity of a cell. In this sense, am olfactory receptor is a protein-molecule that recognizes and responds to endogenous-chemical signals, chemokinesor cytokines e.g. an acetylcholine-receptor recognizes and responds to its endogenous-ligand, acetylcholine. However, sometimes in pharmacology, the term is also used to include other proteins that are drug-targets, such as enzymes, transporters and ion-channels.
-
PropertiesThis MyBioSource Fluorescein isothiocyanate (FITC) antibody is currently after some BD antibodies the most commonly used fluorescent dye for FACS. When excited at 488 nanometers, FITC has a green emission that's usually collected at 530 nanometers, the FL1 detector of a FACSCalibur or FACScan. FITC has a high quantum yield (efficiency of energy transfer from absorption to emission fluorescence) and approximately half of the absorbed photons are emitted as fluorescent light. For fluorescent microscopy applications, the 1 FITC is seldom used as it photo bleaches rather quickly though in flow cytometry applications, its photo bleaching effects are not observed due to a very brief interaction at the laser intercept. MyBioSource FITC is highly sensitive to pH extremes. Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.
-
ConjugationAnti-FITC Antibody
-
TestMouse or mice from the Mus musculus species are used for production of mouse monoclonal antibodies or mabs and as research model for humans in your lab. Mouse are mature after 40 days for females and 55 days for males. The female mice are pregnant only 20 days and can give birth to 10 litters of 6-8 mice a year. Transgenic, knock-out, congenic and inbread strains are known for C57BL/6, A/J, BALB/c, SCID while the CD-1 is outbred as strain.
-
Latin nameMus musculus
-
Gene target
-
Gene symbolNR3C1, NCOA2, ARHGAP35
-
Short nameMOUSE ANTI GLUCOCORTICOID RECEPTOR:FITC
-
Techniqueanti human, Mouse, anti, FITC, antibody to, anti human antibodies, Fluorescein, mouses
-
HostMouse
-
IsotypeIgG1
-
LabelFITC
-
SpeciesHuman, Humans, Mouses
-
Alternative nameMOUSE antibody to H. sapiens GLUCOCORTICOID RECEPTOR:fluorecein
-
Alternative techniquemurine, antibodies, fluorescine
-
Gene info
-
Identity
-
Gene
-
Long gene namenuclear receptor subfamily 3 group C member 1
-
Synonyms gene
-
Synonyms gene name
- nuclear receptor subfamily 3, group C, member 1
- nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)
-
Synonyms
-
Synonyms name
-
GenBank acession
-
Locus
-
Discovery year2001-06-22
-
Entrez gene record
-
Pubmed identfication
-
Classification
- Nuclear receptor subfamily 3 group C
-
VEGA ID
Gene info
-
Identity
-
Gene
-
Long gene namenuclear receptor coactivator 2
-
Synonyms
-
Synonyms name
-
GenBank acession
-
Locus
-
Discovery year1999-12-17
-
Entrez gene record
-
Pubmed identfication
-
Classification
- Lysine acetyltransferases
- Basic helix-loop-helix proteins
-
VEGA ID
Gene info
-
Identity
-
Gene
-
Long gene nameRho GTPase activating protein 35
-
Synonyms gene
-
Synonyms gene name
- glucocorticoid receptor DNA binding factor 1
-
Synonyms
-
GenBank acession
-
Locus
-
Discovery year1993-12-15
-
Entrez gene record
-
Pubmed identfication
-
RefSeq identity
-
Classification
- Rho GTPase activating proteins
-
VEGA ID
MeSH Data
-
Name
-
ConceptScope note: Test for tissue antigen using either a direct method, by conjugation of antibody with fluorescent dye (FLUORESCENT ANTIBODY TECHNIQUE, DIRECT) or an indirect method, by formation of antigen-antibody complex which is then labeled with fluorescein-conjugated anti-immunoglobulin antibody (FLUORESCENT ANTIBODY TECHNIQUE, INDIRECT). The tissue is then examined by fluorescence microscopy.
-
Tree numbers
- E01.370.225.500.607.512.240
- E01.370.225.750.551.512.240
- E05.200.500.607.512.240
- E05.200.750.551.512.240
- E05.478.583.375
-
Qualifiersethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data