MOUSE ANTI HUMAN GLUCOCORTICOID RECEPTOR
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Catalog numberMBS224530
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PricePlease ask
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Size5x0.2 mg
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Products_typeAntibody
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Products_short_name[GLUCOCORTICOID RECEPTOR]
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Other_names[glucocorticoid receptor isoform alpha; Glucocorticoid receptor; glucocorticoid receptor; glucocorticoid nuclear receptor variant 1; nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor); Nuclear receptor subfamily 3 group C member 1]
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Other_gene_names[NR3C1; NR3C1; GR; GCR; GRL; GCCR; GRL; GR]
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ClonalityMonoclonal
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Clone[5E4]
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ReactivityHuman
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SpecificityGLUCOCORTICOID RECEPTOR This item recognises the human glucocorticoid receptor, located in the cytoplasm of cells and associated with certain heat shock proteins.
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FormPurified (Purified IgG - liquid)
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ConcentrationIgG concentration 1 mg/ml
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Storage_stabilityStore at +4 degree C or at -20 degree C if preferred. Storage in frost-free freezers is not recommended. This product should be stored undiluted. This product is photosensitive and should be protected from light. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use. Shelf Life: 18 months from date of dispatch.
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Tested_applicationFlow Cytometry (FACS)
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DescriptionThis antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided. Antibody against the Hu protein or peptide or recombinant supplied in 1 volumes. Ask for quote if you need bulk. The receptors are ligand binding factors of type 1, 2 or 3 and protein-molecules that receive chemical-signals from outside a cell. When such chemical-signals couple or bind to a receptor, they cause some form of cellular/tissue-response, e.g. a change in the electrical-activity of a cell. In this sense, am olfactory receptor is a protein-molecule that recognizes and responds to endogenous-chemical signals, chemokinesor cytokines e.g. an acetylcholine-receptor recognizes and responds to its endogenous-ligand, acetylcholine. However, sometimes in pharmacology, the term is also used to include other proteins that are drug-targets, such as enzymes, transporters and ion-channels.
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PropertiesHuman proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.
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TestMouse or mice from the Mus musculus species are used for production of mouse monoclonal antibodies or mabs and as research model for humans in your lab. Mouse are mature after 40 days for females and 55 days for males. The female mice are pregnant only 20 days and can give birth to 10 litters of 6-8 mice a year. Transgenic, knock-out, congenic and inbread strains are known for C57BL/6, A/J, BALB/c, SCID while the CD-1 is outbred as strain.
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Latin nameMus musculus
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Gene target
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Gene symbolNR3C1, NCOA2, ARHGAP35
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Short nameMOUSE ANTI GLUCOCORTICOID RECEPTOR
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Techniqueanti human, Mouse, anti, antibody to, anti human antibodies, mouses
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HostMouse
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IsotypeIgG1
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SpeciesHuman, Humans, Mouses
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Alternative nameMOUSE antibody to H. sapiens GLUCOCORTICOID RECEPTOR
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Alternative techniquemurine, antibodies
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Gene info
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Identity
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Gene
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Long gene namenuclear receptor subfamily 3 group C member 1
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Synonyms gene
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Synonyms gene name
- nuclear receptor subfamily 3, group C, member 1
- nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)
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Synonyms
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Synonyms name
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GenBank acession
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Locus
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Discovery year2001-06-22
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Entrez gene record
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Pubmed identfication
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Classification
- Nuclear receptor subfamily 3 group C
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VEGA ID
Gene info
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Identity
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Gene
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Long gene namenuclear receptor coactivator 2
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Synonyms
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Synonyms name
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GenBank acession
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Locus
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Discovery year1999-12-17
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Entrez gene record
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Pubmed identfication
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Classification
- Lysine acetyltransferases
- Basic helix-loop-helix proteins
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VEGA ID
Gene info
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Identity
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Gene
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Long gene nameRho GTPase activating protein 35
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Synonyms gene
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Synonyms gene name
- glucocorticoid receptor DNA binding factor 1
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Synonyms
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GenBank acession
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Locus
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Discovery year1993-12-15
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Rho GTPase activating proteins
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VEGA ID
MeSH Data
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Name
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ConceptScope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
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Tree numbers
- E05.196.401.143
- E05.301.300.096
- E05.478.566.320.200
- E05.601.262
- E05.601.470.320.200
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Qualifiersethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data