Mouse Monoclonal [clone JOL2] (IgG1) to Human LMNA / Lamin A/C Antibody
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Catalog numberGEN245432
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PricePlease ask
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Size0.05 ml
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Also known asLMNA / Lamin A/C
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Other nameslamin isoform C; Prelamin-A/C; lamin; 70 kDa lamin; prelamin-A/C; lamin A/C-like 1; renal carcinoma antigen NY-REN-32; lamin A/C; 70 kDa lamin; Renal carcinoma antigen NY-REN-32
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CategoryAntibodies
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SubcategoryMnoclonal antibodies
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Gene nameLMNA
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Gene name synonimsN/A
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Other gene namesLMNA; LMNA; FPL; IDC; LFP; CDDC; EMD2; FPLD; HGPS; LDP1; LMN1; LMNC; PRO1; CDCD1; CMD1A; FPLD2; LMNL1; CMT2B1; LGMD1B; LMN1
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ClonalityMonoclonal
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Immunoglobulin isotypeIgG1
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CloneJOL2
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Host organismMouse (Mus musculus)
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Species reactivityHuman (Homo sapiens); Due to limited knowledge and inability for testing each and every species, the reactivity of the antibody may extend to other species which are not listed hereby.
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Specificity and cross reactivityThe antibody reacts with both recombinant and native Lamin A and C in humans. It has been shown to bind to an epitope between amino acids 464-572; Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited. This particular antibody might cross react with speacies outside of the listed ones.
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Purification methodTissue culture supernatant
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Form AppearanceTissue culture supernatant, 0.2 M Tris/HCl, pH 7.4, 5-10% fetal calf serum. Sourced in TCS.
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ConcentrationN/A
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Storage and shippingFor long term storage, keep the antibody at -20 degrees Celsius. Short term storage of the antibody can be done at +4 degrees Celsius. Cycles of freezing/defrosting can damage the peptide chains of the antibodies thus reducing the activity.
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Tested applicationsImmunohistochemistry (IHC - Paraffin), Western Blot (WB), Immunoprecipitation (IP), Flow Cytometry (FC/FACS)
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PropertiesIf you buy Antibodies supplied by MBS Monoclonals they should be stored frozen at - 24°C for long term storage and for short term at + 5°C. Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.
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AboutMonoclonals of this antigen are available in different clones. Each murine monoclonal anibody has his own affinity specific for the clone. Mouse monoclonal antibodies are purified protein A or G and can be conjugated to FITC for flow cytometry or FACS and can be of different isotypes.
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TestMouse or mice from the Mus musculus species are used for production of mouse monoclonal antibodies or mabs and as research model for humans in your lab. Mouse are mature after 40 days for females and 55 days for males. The female mice are pregnant only 20 days and can give birth to 10 litters of 6-8 mice a year. Transgenic, knock-out, congenic and inbread strains are known for C57BL/6, A/J, BALB/c, SCID while the CD-1 is outbred as strain.
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Latin nameMus musculus
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French translationanticorps
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Gene target
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Gene symbolLMNA
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Short nameMouse Monoclonal [clone JOL2] (IgG1) LMNA / Lamin A/C Antibody
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TechniqueMouse monoclonal, Antibody, Mouse, antibodies against human proteins, antibodies for, Monoclonals or monoclonal antibodies, mouses, mouse monoclonals
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Hostmouse monoclonal, Murine monoclonal antibodies or Mabs are often conjugated and the isotype is IgG.
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IsotypeIgG1
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SpeciesHuman, Humans, Mouses
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Alternative nameAnti-Mouse Monoclonal [clone JOL2] (IgG1) to Human LMNA / Lamin A/C
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Alternative techniqueantibodies, murine
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Clone nameJOL2
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Gene info
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Identity
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Gene
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Long gene namelamin A/C
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Synonyms gene
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Synonyms gene name
- cardiomyopathy, dilated 1A (autosomal dominant)
- limb girdle muscular dystrophy 1B (autosomal dominant)
- progeria 1 (Hutchinson-Gilford type)
- lamin A/C-like 1
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Synonyms
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Synonyms name
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GenBank acession
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Locus
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Discovery year1992-04-09
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Lamins
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VEGA ID
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Locus Specific Databases
MeSH Data
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Name
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ConceptScope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
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Tree numbers
- E05.196.401.143
- E05.301.300.096
- E05.478.566.320.200
- E05.601.262
- E05.601.470.320.200
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Qualifiersethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data