Mouse Monoclonal [clone JOL2] (IgG1) to Human LMNA / Lamin A/C
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Catalog numberMBS245432
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PricePlease ask
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Size0.05 mL
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Products_typeAntibody
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Products_short_name[LMNA / Lamin A/C]
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Products_name_syn[Anti-LMNA / Lamin A/C Antibody (aa464-572, clone JOL2) IHC-plus; LMNA; 70 kDa lamin; CDCD1; CMD1A; EMD2; FPLD; IDC; FPL; FPLD2; Lamin A/C; Lamin; LFP; LMNC; LMN1; LMNL1; HGPS; Prelamin-A/C; PRO1; Lamin A; Lamin A/C-like 1; LGMD1B; CDDC; CMT2B1; LDP1; Human LMNA; Lamin A/C]
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Other_names[lamin isoform C; Prelamin-A/C; lamin; 70 kDa lamin; prelamin-A/C; lamin A/C-like 1; renal carcinoma antigen NY-REN-32; lamin A/C; 70 kDa lamin; Renal carcinoma antigen NY-REN-32]
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Products_gene_name[LMNA]
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Other_gene_names[LMNA; LMNA; FPL; IDC; LFP; CDDC; EMD2; FPLD; HGPS; LDP1; LMN1; LMNC; PRO1; CDCD1; CMD1A; FPLD2; LMNL1; CMT2B1; LGMD1B; LMN1]
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ClonalityMonoclonal
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Clone[JOL2]
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ReactivityHuman
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SpecificityThe antibody reacts with both recombinant and native Lamin A and C in humans. It has been shown to bind to an epitope between amino acids 464-572
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PurityTissue culture supernatant
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FormTissue culture supernatant, 0.2 M Tris/HCl, pH 7.4, 5-10% fetal calf serum. Sourced in TCS.
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Storage_stabilityLong term: -20 degree C; Short term: +4 degree C. Avoid repeat freeze-thaw cycles.
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Tested_applicationImmunohistochemistry (IHC - Paraffin), Western Blot (WB), Immunoprecipitation (IP), Flow Cytometry (FC/FACS)
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PropertiesHuman proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.
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AboutMonoclonals of this antigen are available in different clones. Each murine monoclonal anibody has his own affinity specific for the clone. Mouse monoclonal antibodies are purified protein A or G and can be conjugated to FITC for flow cytometry or FACS and can be of different isotypes.
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TestMouse or mice from the Mus musculus species are used for production of mouse monoclonal antibodies or mabs and as research model for humans in your lab. Mouse are mature after 40 days for females and 55 days for males. The female mice are pregnant only 20 days and can give birth to 10 litters of 6-8 mice a year. Transgenic, knock-out, congenic and inbread strains are known for C57BL/6, A/J, BALB/c, SCID while the CD-1 is outbred as strain.
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Latin nameMus musculus
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Gene target
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Gene symbolLMNA
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Short nameMouse Monoclonal [clone JOL2] (IgG1) LMNA / Lamin A/C
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TechniqueMouse monoclonal, Mouse, Monoclonals or monoclonal antibodies, mouses, mouse monoclonals
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HostMouse, Murine monoclonal antibodies or Mabs are often conjugated and the isotype is IgG.
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IsotypeIgG1, IgG1
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SpeciesHuman, Humans, Mouses
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Alternative nameMouse monoclonal [clonality JOL2] (IgG1) to H. sapiens LMNA / Lamin A/C
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Alternative techniquemurine
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Clone nameJOL2
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Gene info
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Identity
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Gene
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Long gene namelamin A/C
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Synonyms gene
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Synonyms gene name
- cardiomyopathy, dilated 1A (autosomal dominant)
- limb girdle muscular dystrophy 1B (autosomal dominant)
- progeria 1 (Hutchinson-Gilford type)
- lamin A/C-like 1
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Synonyms
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Synonyms name
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GenBank acession
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Locus
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Discovery year1992-04-09
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Lamins
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VEGA ID
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Locus Specific Databases