Rat Anti-Mouse BP-1/Ly-51-PE

  • Catalog number
    GEN673493
  • Price
    Please ask
  • Size
    100ug
  • Also known as
    BP-1 (Ly-51, 6C3)
  • Other names
    N/A
  • Category
    Secondary Antibodies
  • Subcategory
    Mnoclonal antibodies
  • Gene name
    N/A
  • Gene name synonims
    N/A
  • Other gene names
    N/A
  • Clonality
    Monoclonal
  • Immunoglobulin isotype
    Rat IgG1 kappa
  • Clone
    FG35.4
  • Host organism
    Rat (Rattus norvegicus)
  • Species reactivity
    Mouse (Mus musculus); Due to limited knowledge and inability for testing each and every species, the reactivity of the antibody may extend to other species which are not listed hereby.
  • Specificity and cross reactivity
    BP-1/Ly-51/6C3 antigen, (aminopeptidase A, E.C.3.4.11.7, glutamylaminopeptidase) BP-1, also known as Ly-51/6C3 antigen, is a type II homodimeric transmembrane glycoprotein formed by two disulfide-linked chains of 140 kDa.1, 2 Originally identified on the surface of pre-B cell lymphomas1, 3 the cDNA encoding BP-1/Ly-51/6C3 has been cloned and found to represent aminopeptidase A.4, 5 It is expressed at high levels on bone marrow stromal cell lines which support in vitro B lymphopoiesis and on a wide variety of mouse tissues known to possess aminopeptidase activity.6-8 Subsets of normal bone marrow pre-B and B cells express low levels of BP-1/Ly-51/6C3, which is rapidly upregulated on pre-B cells in the presence of IL- 7.9, 10 The BP-1/6C3 marker is commonly used to identify B cells in different stages of development.11; Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited. This particular antibody might cross react with speacies outside of the listed ones.
  • Purification method
    N/A
  • Form Appearance
    R - phycoerythrin (R - PE) Conjugate
  • Concentration
    N/A
  • Storage and shipping
    The purified (UNLB) antibody is supplied as 0.5 mg of purified immunoglobulin in 1.0 mL of 100 mM borate buffered saline, pH 8.2. No preservatives or amine-containing buffer salts added. Store the antibody ats should be kept in the range of 1-7 degrees Celsius.. The fluorescein (FITC) conjugate is supplied as 0.5 mg in 1.0 mL of PBS/NaN3. Store the antibody ats should be kept in the range of 1-7 degrees Celsius.. The biotin (BIOT) conjugate is supplied as 0.5 mg in 1.0 mL of PBS/NaN3. Store the antibody ats should be kept in the range of 1-7 degrees Celsius.. The R-phycoerythrin (R-PE) conjugate is supplied as 0.1 mg in 1.0 mL or 0.2 mg in 2.0 mL of PBS/NaN3 and a stabilizing agent. Store the antibody ats should be kept in the range of 1-7 degrees Celsius.. Do not freeze! Protect conjugated forms from light. Each reagent is stable for the period shown on the bottle label if stored as directed.
  • Tested applications
    Flow Cytometry; Immunoprecipitation
  • Description
    This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided. Antibody for research use.
  • Test
    Mouse or mice from the Mus musculus species are used for production of mouse monoclonal antibodies or mabs and as research model for humans in your lab. Mouse are mature after 40 days for females and 55 days for males. The female mice are pregnant only 20 days and can give birth to 10 litters of 6-8 mice a year. Transgenic, knock-out, congenic and inbread strains are known for C57BL/6, A/J, BALB/c, SCID while the CD-1 is outbred as strain.
  • Latin name
    Mus musculus, Rattus norvegicus
  • About
    Rats are used to make rat monoclonal anti mouse antibodies. There are less rat- than mouse clones however. Rats genes from rodents of the genus Rattus norvegicus are often studied in vivo as a model of human genes in Sprague-Dawley or Wistar rats.
  • Gene target
  • Gene symbol
    IGHV8-51-1, ETV3, IGHVII-51-2, IGLV1-51, NAE1, IGHV5-51, SIGMAR1, ERF, LINC00665, TSPOAP1
  • Short name
    Anti-Mouse BP-1/Ly-51-PE
  • Technique
    anti-, Mouse, anti, antibody to, antibodies, mouses
  • Host
    Rat
  • Label
    PE
  • Species
    Mouse, Mouses, Rats
  • Alternative name
    Anti-Rat Anti-Mouse BP-1/Ly-51-PE
  • Alternative technique
    murine, antibodies
Gene info
  • Identity
  • Gene
  • Long gene name
    immunoglobulin heavy variable IGHV8-51-1 (non-functional)
  • Synonyms gene
  • Synonyms gene name
    • immunoglobulin heavy variable (III)-51-1
    • immunoglobulin heavy variable (III)-51-1 pseudogene
    • immunoglobulin heavy variable (III)-51-1 (pseudogene)
    • immunoglobulin heavy variable IGHV8-51-1 (pseudogene)
  • Synonyms
  • GenBank acession
  • Locus
  • Discovery year
    2000-04-17
  • Entrez gene record
  • RefSeq identity
  • Classification
    • Immunoglobulin heavy locus at 14q32.33
  • VEGA ID
Gene info
  • Identity
  • Gene
  • Long gene name
    ETS variant transcription factor 3
  • Synonyms gene name
    • ets variant gene 3, ETS family transcriptional repressor
    • ETS variant 3
  • Synonyms
  • GenBank acession
  • Locus
  • Discovery year
    1994-12-15
  • Entrez gene record
  • Pubmed identfication
  • RefSeq identity
  • Classification
    • ETS transcription factor family
  • VEGA ID
Gene info
  • Identity
  • Gene
  • Long gene name
    immunoglobulin heavy variable (II)-51-2 (pseudogene)
  • Synonyms gene name
    • immunoglobulin heavy variable (II)-51-2
    • immunoglobulin heavy variable (II)-51-2 pseudogene
  • Synonyms
  • GenBank acession
  • Locus
  • Discovery year
    2000-04-17
  • Entrez gene record
  • RefSeq identity
  • Classification
    • Immunoglobulin heavy locus at 14q32.33
  • VEGA ID
Gene info
Gene info
Gene info
Gene info
Gene info
Gene info
Gene info
MeSH Data
  • Name
  • Concept
    Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
  • Tree numbers
    • E05.196.401.143
    • E05.301.300.096
    • E05.478.566.320.200
    • E05.601.262
    • E05.601.470.320.200
  • Qualifiers
    ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data
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