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Also known as
Thymopoietin
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Other names
thymopoietin isoform alpha; Lamina-associated polypeptide 2, isoform alpha; thymopoietin; TP alpha; TP beta/gamma; LEM domain containing 4; lamina-associated polypeptide 2; thymopoietin-related peptide isoform alpha; thymopoietin-related peptide isoforms beta/gamma; thymopoietin; Thymopoietin isoform alpha; TP alpha; Thymopoietin-related peptide isoform alpha; TPRP isoform alphaCleaved into the following 2 chains:Thymopoietin; TP; Alternative name(s):; SpleninThymopentin; Alternative name(s):; TP5
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Category
Antibodies
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Subcategory
Mnoclonal antibodies
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Gene name
TMPO; TMPO; TP; LAP2; CMD1T; LEMD4; PRO0868; LAP2; TP alpha; TPRP isoform alpha; TP
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Gene name synonims
TMPO; TMPO; TP; LAP2; CMD1T; LEMD4; PRO0868; LAP2; TP alpha; TPRP isoform alpha; TP
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Other gene names
TMPO; TMPO; TP; LAP2; CMD1T; LEMD4; PRO0868; LAP2; TP alpha; TPRP isoform alpha; TP
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Clonality
Monoclonal
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Immunoglobulin isotype
IgG1
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Clone
(#8S37)
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Host organism
Mouse (Mus musculus)
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Species reactivity
Human (Homo sapiens); Due to limited knowledge and inability for testing each and every species, the reactivity of the antibody may extend to other species which are not listed hereby.
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Specificity and cross reactivity
N/A; Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited. This particular antibody might cross react with speacies outside of the listed ones.
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Purification method
N/A
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Form Appearance
Lyophilized
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Concentration
N/A
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Storage and shipping
Lyophilized samples are stable for 2 years from date of receipt when stored at -70 degree C. Reconstituted antibody can be aliquoted and stored frozen at < Store the antibody at -20 degrees Celsius. for at least for six months without detectable loss of activity.
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Tested applications
Western Blot (WB)
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Description
This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided. Antibody for research use.
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Test
MBS Monoclonals supplies antibodies that are for research of human proteins. Mouse or mice from the Mus musculus species are used for production of mouse monoclonal antibodies or mabs and as research model for humans in your lab. Mouse are mature after 40 days for females and 55 days for males. The female mice are pregnant only 20 days and can give birth to 10 litters of 6-8 mice a year. Transgenic, knock-out, congenic and inbread strains are known for C57BL/6, A/J, BALB/c, SCID while the CD-1 is outbred as strain.
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Properties
Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.
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Latin name
Mus musculus
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Gene
Thymopoietin I and II are proteins involved in the induction of CD90 in the thymus. The thymopoetin (TMPO) gene encodes three alternatively spliced mRNAs encoding proteins of 75 kDa (alpha), 51 kDa (beta) and 39 kDa (gamma) which are ubiquitously expressed in all cells. The human TMPO gene maps to chromosome band 12q22 and consists of eight exons. TMPO alpha is present diffusely expressed with the cell nucleus while TMPO beta and gamma are localized to the nuclear membrane. TMPO beta is a human homolog of the murine protein LAP2. LAP2 plays a role in the regulation of nuclear architecture by binding lamin B1 and chromosomes. This interaction is regulated by phosphorylation during mitosis. Given the nuclear localization of the three TMPO isoforms, it is unlikely that these proteins play any role in CD90 induction.
