MHC Class 1 Chain-related Gene A, B (MHC Class 1 Chain-related Gene A, MHC Class I Polypeptide-related Sequence A, MICA, MIC-A, MHC Class 1 Chain-related Gene B, MHC Class I Polypeptide-related Sequence B, MICB, MIC-B, PERB11.1, PERB11.2) (Biotin)

  • Catalog number
    GEN606876
  • Price
    Please ask
  • Size
    100ug
  • Also known as
    MHC Class 1 Chain-related Gene A, B
  • Other names
    MHC class I chain-related protein B, partial; N/A
  • Category
    Antibodies
  • Subcategory
    Mnoclonal antibodies
  • Gene name
    N/A
  • Gene name synonims
    N/A
  • Other gene names
    N/A
  • Clonality
    Monoclonal
  • Immunoglobulin isotype
    IgG2a
  • Clone
    10F158
  • Host organism
    Mouse (Mus musculus)
  • Source organism
    Human (Homo sapiens)
  • Species reactivity
    Human (Homo sapiens); Due to limited knowledge and inability for testing each and every species, the reactivity of the antibody may extend to other species which are not listed hereby.
  • Specificity and cross reactivity
    Recognizes human nonclassical MHC class I chain A (MICA) and nonclassical MHC class I chain MICB (MICB). Reported to inhibit the cytotoxicity of NK cells stimulated by IFN alpha-treated dendritic cells.; Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited. This particular antibody might cross react with speacies outside of the listed ones.
  • Purification method
    Affinity Purified by Protein G affinity chromatography.
  • Form Appearance
    Supplied as a liquid in PBS, pH 7.4, 1% BSA, 0.09% sodium azide. Labeled with Biotin.
  • Concentration
    N/A
  • Storage and shipping
    Store the antibody at +4 degrees Celsius for short term storage.. Aliquot to avoid repeated freezing and thawing. For optimal long term storage, the antibody should be kept at -20 degrees Celsius. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
  • Tested applications
    Immunohistochemistry (IHC), Flow Cytometry (FC/FACS)
  • Properties
    Biotin conjugates can be detected by horseradish peroxidase, alkaline phosphatase substrates or anti biotin conjugated antibodies. Avidin and Streptavidin bind to the small biotin and are couple to HRP or AP for ELISA. To break the streptavidin Biotin bond we suggest to use a 6 molar guanidine HCl solution with acidity of pH 1.6.
  • Conjugation
    Biotinylated
  • Description
    cDNA genes are a locus (or region) of DNA for functional transcript RNA or protein. An ELISA is used to detect the expressed protein in biological fluids, serum, saliva.
  • Gene target
  • Gene symbol
    MICB, MICA-AS1, MICA, MICB-DT, HCG9, GDF15, PURG, SP140, KLRC1, EXOG
  • Short name
    MHC Class 1 Chain- A, B (MHC Class 1 Chain- A, MHC Class I Polypeptide- Sequence A, MICA, MIC-A, MHC Class 1 Chain- B, MHC Class I Polypeptide- Sequence B, MICB, MIC-B, PERB11 1, PERB11 2) ( )
  • Label
    Biotin
  • Alternative name
    Anti-MHC Class 1 Chain-related Gene A, B (MHC Class 1 Chain-related Gene A, MHC Class I Polypeptide-related Sequence A, MICA, MIC-A, MHC Class 1 Chain-related Gene B, MHC Class I Polypeptide-related Sequence B, MICB, MIC-B, PERB11.1, PERB11.2) (Biotin)
  • Alternative to gene target
    MHC class I polypeptide-related sequence A, MICA and IDBG-77578 and ENSG00000204520 and 100507436, protein binding, Plasma membranes
Gene info
Gene info
Gene info
Gene info
Gene info
Gene info
Gene info
Gene info
Gene info
Gene info
MeSH Data
  • Name
  • Concept
    Scope note: A multistage process that includes cloning, physical mapping, subcloning, determination of the DNA SEQUENCE, and information analysis.
  • Tree numbers
    • E05.393.760.700
  • Qualifiers
    ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data
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