M-CSF Receptor(Tyr546) Antibody, ALEXA FLUOR 647
-
Catalog numberbs-3074R-A647
-
PricePlease ask
-
Size100ul
-
-
Long nameM-CSF Receptor(Tyr546) Antibody, ALEXA FLUOR 647 Conjugated
-
Also known asAnti-M-CSF Receptor Tyr546 PAb ALEXA FLUOR 647
-
CategoryConjugated Primary Antibodies
-
Conjugated withALEXA FLUOR® 647
-
Host OrganismRabbit (Oryctolagus cuniculus)
-
Target AntigenM-CSF Receptor Tyr546
-
SpecificityThis is a highly specific antibody against M-CSF Receptor Tyr546.
-
ModificationPhosphorylation
-
Modification SiteTyr546
-
ClonalityPolyclonal
-
ClonePolyclonal antibody
-
Concentration1ug per 1ul
-
SourceKLH conjugated synthetic phosphopeptide derived from human CSF1R around the phosphorylation site of tyrosine 546
-
Gene ID Number1436
-
Tested applicationsIF(IHC-P)
-
Recommended dilutionsIF(IHC-P)(1:50-200)
-
CrossreactivityHuman, Mouse, Rat
-
Cross reactive species detailsDue to limited amount of testing and knowledge, not every possible cross-reactivity is known.
-
Background of the antigenThis protein tyrosine kinase transmembrane receptor is the receptor for colony stimulating factor 1, a cytokine which controls the production, differentiation, and function of macrophages. This receptor mediates most if not all of the biological effects of this cytokine. Ligand binding activates the receptor kinase through a process of oligomerization and transphosphorylation. The encoded protein is a member of the CSF1/PDGF receptor family of tyrosine protein kinases and contains 5 immunoglobulin like C2 type domains. CD115 is expressed by cells of the monocytic lineage and by progenitor cells. Mutations in this gene have been associated with a predisposition to myeloid malignancy.
-
PurificationPurified by Protein A.
-
Storage conditionsStore this antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Keep refrigerated at 2 to 8 degrees Celcius for up to one year.
-
Excitation emission650nm/665nm
-
SynonymsC FMS; CD 115; CD115; CD115 antigen; CFMS; Colony stimulating factor 1 receptor; Colony stimulating factor I receptor; CSF 1 R; CSF 1R; CSF1 R; CSF1R; CSFR; FIM 2; FIM2; CSF1R_HUMAN
-
PropertiesFor facs or microscopy Alexa 1 conjugate. Alexa Fluor 633 is a practical alternative to APC as well as Cy5. Bioss Primary Conjugated Antibodies. ALEXA FLUOR made this Alexa Fluor 633 conjugate that can be used in multi-color flow cytometry with instruments equipped with a second red laser or red diode. It is detected in the FL4 detector of the core's upgraded 2-laser FACScans. Like other Alexa Fluor dyes, the Anti-M-CSF Receptor Tyr546 exhibits uncommon photo stability, making it an ideal choice for fluorescent microscopy. If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies. ALEXA FLUOR they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
-
ConjugationAlexa Fluor, ALEXA FLUOR 647
-
DescriptionThe receptors are ligand binding factors of type 1, 2 or 3 and protein-molecules that receive chemical-signals from outside a cell. When such chemical-signals couple or bind to a receptor, they cause some form of cellular/tissue-response, e.g. a change in the electrical-activity of a cell. In this sense, am olfactory receptor is a protein-molecule that recognizes and responds to endogenous-chemical signals, chemokinesor cytokines e.g. an acetylcholine-receptor recognizes and responds to its endogenous-ligand, acetylcholine. However, sometimes in pharmacology, the term is also used to include other proteins that are drug-targets, such as enzymes, transporters and ion-channels.
-
French translationanticorps
-
Gene target
-
Gene symbolCSF1, CPT1B, CSF2, IRAK3, PGAM2, CYP20A1, USP16, CYB5B, H3C14, CSF3
-
Short nameAnti-M-CSF Receptor Tyr546
-
TechniqueAntibody, antibodies against human proteins, antibodies for
-
IsotypeImmunoglobulin G (IgG)
-
LabelALEXA FLUOR 647
-
Alternative nameM-CSF Receptor(Tyr546) Antibody, ALEXA FLUOR 647
-
Alternative techniqueantibodies
-
Gene info
-
Identity
-
Gene
-
Long gene namecolony stimulating factor 1
-
Synonyms gene name
- colony stimulating factor 1 (macrophage)
-
Synonyms
-
Synonyms name
-
GenBank acession
-
Locus
-
Discovery year1986-01-01
-
Entrez gene record
-
Pubmed identfication
-
RefSeq identity
-
VEGA ID
Gene info
-
Identity
-
Gene
-
Long gene namecarnitine palmitoyltransferase 1B
-
Synonyms gene name
- carnitine palmitoyltransferase 1B (muscle)
-
Synonyms
-
Synonyms name
-
GenBank acession
-
Locus
-
Discovery year1996-08-14
-
Entrez gene record
-
Pubmed identfication
-
RefSeq identity
-
VEGA ID
Gene info
-
Identity
-
Gene
-
Long gene namecolony stimulating factor 2
-
Synonyms gene name
- colony stimulating factor 2 (granulocyte-macrophage)
-
Synonyms
-
Synonyms name
-
GenBank acession
-
Locus
-
Discovery year2001-06-22
-
Entrez gene record
-
Pubmed identfication
-
RefSeq identity
-
VEGA ID
Gene info
-
Identity
-
Gene
-
Long gene nameinterleukin 1 receptor associated kinase 3
-
Synonyms gene name
- interleukin-1 receptor-associated kinase 3
-
Synonyms
-
GenBank acession
-
Locus
-
Discovery year2002-07-17
-
Entrez gene record
-
Pubmed identfication
-
Classification
- MicroRNA protein coding host genes
-
VEGA ID
Gene info
-
Identity
-
Gene
-
Long gene namephosphoglycerate mutase 2
-
Synonyms gene name
- phosphoglycerate mutase 2 (muscle)
-
Synonyms
-
Locus
-
Discovery year1989-06-30
-
Entrez gene record
-
Classification
- Phosphoglycerate mutases
- Bisphosphoglycerate phosphatases
-
VEGA ID
Gene info
-
Identity
-
Gene
-
Long gene namecytochrome P450 family 20 subfamily A member 1
-
Synonyms gene name
- cytochrome P450, family 20, subfamily A, polypeptide 1
-
Synonyms
-
GenBank acession
-
Locus
-
Discovery year2003-03-20
-
Entrez gene record
-
RefSeq identity
-
Classification
- Cytochrome P450 family 20
-
VEGA ID
Gene info
-
Identity
-
Gene
-
Long gene nameubiquitin specific peptidase 16
-
Synonyms gene name
- ubiquitin specific protease 16
-
Synonyms
-
GenBank acession
-
Locus
-
Discovery year1999-07-09
-
Pubmed identfication
-
Classification
- Ubiquitin specific peptidases
-
VEGA ID
Gene info
-
Identity
-
Gene
-
Long gene namecytochrome b5 type B
-
Synonyms gene name
- cytochrome b5 type B (outer mitochondrial membrane)
-
Synonyms
-
Locus
-
Discovery year2006-01-30
-
Entrez gene record
-
Pubmed identfication
-
RefSeq identity
-
VEGA ID
Gene info
-
Identity
-
Gene
-
Long gene nameH3 clustered histone 14
-
Synonyms gene
-
Synonyms gene name
- H3 histone family, member M
- histone 2, H3c
- histone cluster 2, H3c
- histone cluster 2 H3 family member c
-
Synonyms
-
GenBank acession
-
Locus
-
Discovery year2003-02-19
-
Entrez gene record
-
Pubmed identfication
-
RefSeq identity
-
Classification
- H3 histones
-
VEGA ID
Gene info
-
Identity
-
Gene
-
Long gene namecolony stimulating factor 3
-
Synonyms gene
-
Synonyms gene name
- chromosome 17 open reading frame 33
- colony stimulating factor 3 (granulocyte)
-
Synonyms
-
Synonyms name
-
Locus
-
Discovery year2001-06-22
-
Entrez gene record
-
Pubmed identfication
-
RefSeq identity
-
Classification
- Receptor ligands
-
VEGA ID
MeSH Data
-
Name
-
ConceptScope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
-
Tree numbers
- E05.196.401.143
- E05.301.300.096
- E05.478.566.320.200
- E05.601.262
- E05.601.470.320.200
-
Qualifiersethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data