IKK epsilon Antibody (IKKE)
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Catalog numberF51063-0.08ML
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PricePlease ask
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Size0.08 ml
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CategoryAntibody
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ConcentrationIn 1X PBS, pH 7.4, with 0.09% sodium azide
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FormAntigen affinity purified
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ConjugationUnconjugated
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ClonePolyclonal antibody
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Recognised antigenIKK epsilon (IKKE)
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Host animalRabbit (Oryctolagus cuniculus)
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ClonalityPolyclonal (rabbit origin)
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Species reactivityHuman (Homo sapiens) ; Due to limited knowledge and inability to test the antibody against all known species, we cannot guarantee that no other cross reactivity can occur.
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Tested applicationsWB, IHC, ELISA
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Recommended dilutionsWestern blot: 1:1000,IHC (Paraffin): 1:50-1:100
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NotesTitration of the IKKE antibody may be required due to differences in protocols and secondary/substrate sensitivity.
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Intented useThis IKKE antibodyis to be used only for research purposes and not for diagnostics..
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UniprotQ14164
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PurityAntigen affinity
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DescriptionProtein kinases are enzymes that transfer a phosphate group from a phosphate donor, generally the g phosphate of ATP, onto an acceptor amino acid in a substrate protein. By this basic mechanism, protein kinases mediate most of the signal transduction in eukaryotic cells, regulating cellular metabolism, transcription, cell cycle progression, cytoskeletal rearrangement and cell movement, apoptosis, and differentiation. With more than 500 gene products, the protein kinase family is one of the largest families of proteins in eukaryotes. The family has been classified in 8 major groups based on sequence comparison of their tyrosine (PTK) or serine/threonine (STK) kinase catalytic domains. The AGC kinase group consists of 63 kinases including the cyclic nucleotide-regulated protein kinase (PKA & PKG) family, the diacylglycerol-activated/phospholipid-dependent protein kinase C (PKC) family, the related to PKA and PKC (RAC/Akt) protein kinase family, the kinases that phosphorylate G protein-coupled receptors family (ARK), and the kinases that phosphorylate ribosomal protein S6 family (RSK).
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ImmunogenA portion of amino acids 686-716 from the human protein was used as the immunogen for this IKKE antibody.
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StorageAliquot the IKKE antibody and store frozen at -20 deg. Celcius or lower. Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity. Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized.
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PropertiesIf you buy Antibodies supplied by NJS poly they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
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French translationanticorps
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Gene target
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Gene symbolIKBKE, IKBKB, CHUK, IKBKG
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Short nameAnti-IKK epsilon (IKKE)
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TechniqueAntibody, antibodies against human proteins, antibodies for
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IsotypeRabbit Ig
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Alternative nameAntibodies to IKK epsilon (IKKE)
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Alternative techniqueantibodies
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Gene info
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Identity
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Gene
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Long gene nameinhibitor of nuclear factor kappa B kinase subunit epsilon
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Synonyms gene name
- inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon
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Synonyms
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GenBank acession
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Locus
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Discovery year2002-12-02
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Entrez gene record
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Pubmed identfication
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Classification
- I kappa B kinases
- MicroRNA protein coding host genes
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VEGA ID
Gene info
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Identity
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Gene
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Long gene nameinhibitor of nuclear factor kappa B kinase subunit beta
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Synonyms gene name
- inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta
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Synonyms
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GenBank acession
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Locus
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Discovery year1998-02-11
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Entrez gene record
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Pubmed identfication
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Classification
- I kappa B kinases
- IKK complex
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VEGA ID
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Locus Specific Databases
Gene info
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Identity
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Gene
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Long gene namecomponent of inhibitor of nuclear factor kappa B kinase complex
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Synonyms gene
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Synonyms gene name
- conserved helix-loop-helix ubiquitous kinase
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Synonyms
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Synonyms name
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GenBank acession
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Locus
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Discovery year1995-03-15
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- I kappa B kinases
- IKK complex
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VEGA ID
Gene info
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Identity
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Gene
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Long gene nameinhibitor of nuclear factor kappa B kinase regulatory subunit gamma
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Synonyms gene
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Synonyms gene name
- incontinentia pigmenti
- inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma
- inhibitor of nuclear factor kappa B kinase subunit gamma
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Synonyms
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Synonyms name
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GenBank acession
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Locus
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Discovery year1998-09-30
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Zinc fingers C2HC-type
- IKK complex
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VEGA ID
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Locus Specific Databases
MeSH Data
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Name
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ConceptScope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
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Tree numbers
- E05.196.401.143
- E05.301.300.096
- E05.478.566.320.200
- E05.601.262
- E05.601.470.320.200
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Qualifiersethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data