FMRP (Ser500) Antibody

• Catalog number
  bs-13188R
• Price
  Please ask
• Size
  0.1ml

• Long name
  FMRP (Ser500) Primary Polyclonal Antibody
• Also known as
  FMRP (Ser500) PAb
• Category
  Primary Antibodies
• Conjugation
  Unconjugated
• Target Antigen
  FMRP Ser500
• Specificity
  This is a highly specific antibody against FMRP Ser500.
• Modification s
  Phosphorylation
• Modification site s
  Ser500
• Clonality
  Polyclonal antibody
• Clone number
  Polyclonal antibody
• Concentration
  1ug per 1ul
• Immunogen range
  480-530/632
• Subcellular location
  Cytoplasm, Nucleus
• Source
  KLH conjugated synthetic phosphopeptide derived from human FMRP around the phosphorylation site of Ser500
• Gene ID number
  2332
• Swiss Prot
  Q06787
• Tested Applications
  WB, IHC-P, IF(IHC-P)
• Recommended dilutions
  WB(1:100-1000), IHC-P(1:100-500), IF(IHC-P)(1:50-200)
• Cross reactivity
  Human, Mouse, Rat
• Cross reactive species details
  Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.
• Background of the target antigen
  Translation repressor. Component of the CYFIP1-EIF4E-FMR1 complex which binds to the mRNA cap and mediates translational repression. In the CYFIP1-EIF4E-FMR1 complex this subunit mediates translation repression (By similarity). RNA-binding protein that plays a role in intracellular RNA transport and in the regulation of translation of target mRNAs. Associated with polysomes. May play a role in the transport of mRNA from the nucleus to the cytoplasm. Binds strongly to poly(G), binds moderately to poly(U) but shows very little binding to poly(A) or poly(C).
• Purification method
  This antibody was purified via Protein A.
• Storage conditions
  Keep the antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store at -20°C for up to 1 year.
• Synonym names
  POF; FMRP; POF1; FRAXA; Fragile X mental retardation protein 1; Protein FMR-1; FMR1
• Properties
  If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• French translation
  anticorps

• Gene target
  FMRP   Ser500  
• Gene symbol
  FMR1
• Short name
  Anti-FMRP Ser500
• Technique
  Antibody, antibodies against human proteins, antibodies for
• Host
  Rabbit (Oryctolagus cuniculus)
• Isotype
  Immunoglobulin G (IgG)
• Alternative name
  FMRP (Ser500) Polyclonal Antibody
• Alternative technique
  antibodies

Gene info

• Identity
  HGNC:3775
• Gene
  FMR1
• Long gene name
  FMRP translational regulator 1
• Synonyms gene
  • POF1
  • POF
• Synonyms gene name
  • premature ovarian failure 1
  • fragile X mental retardation 1
• Synonyms
  • FMRP
  • FRAXA
  • MGC87458
• GenBank acession
  • X69962
• Locus
  Xq27.3
• Discovery year
  1992-01-17
• Entrez gene record
  2332
• Pubmed identfication
  • 1572655
• RefSeq identity
  • NM_002024
• VEGA ID
  OTTHUMG00000022606
• Locus Specific Databases
  • Global Variome shared LOVD
  • LRG_762

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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