Fingolimod (FTY-720A, FTY720)
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Catalog number
1618-25
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Price
Please ask
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Size
25 mg
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Alternative_name
FTY-720A, FTY720
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Description
FTY720 can be phosphorylated by sphingosine kinase, which then acts as a potent agonist at four of the sphingosine-1-phosphate (S1P) receptors (S1P1, S1P3, S1P4, and S1P5). IC₅₀ of (S)- and (R)- FTY720-phosphate on lymphocyte migration toward 10 nM of S1P are 0.137 nM and 10.98 nM respectively. The IC₅₀ values to cell lines MCF-7 is 6.8±0.6 µM.
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CAS Number
162359-56-0
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Structure Available
Yes
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Salt Form
No
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Molecular Formula
C₁₉H₃₃NO₂.HCl
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Molecular Weight
343.93
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Cell Permeable
Yes
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Purity
≥98% by HPLC
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Solubilities
DMSO (100 mg/ml) of EtOH (100 mg/ml)
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Handling
Protect from air and moisture
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Tag Line
A novel immune modulator
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Storage Condition
-20°C
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Shipping Condition
RT
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Shelf Life
24months
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MDL Number
MFCD00939512
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PubChem CID
107969
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SMILES
CCCCCCCCC1=CC=C(C=C1)CCC(CO)(CO)N.Cl
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InChi
InChI=1S/C19H33NO2.ClH/c1-2-3-4-5-6-7-8-17-9-11-18(12-10-17)13-14-19(20,15-21)16-22;/h9-12,21-22H,2-8,13-16,20H2,1H3;1H
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InChi Key
SWZTYAVBMYWFGS-UHFFFAOYSA-N
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MSDS Available
Yes
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Gene target
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Short name
Fingolimod (FTY-720A, FTY720)
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Alternative name
Fingolimod (FTY-720A, FTY720)
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