c-ABL(Tyr204) Antibody
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Catalog numberbs-10353R
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PricePlease ask
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Size0.1ml
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Long namec-ABL(Tyr204) Primary Polyclonal Antibody
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Also known asc-ABL(Tyr204) PAb
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CategoryPrimary Antibodies
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ConjugationUnconjugated
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Target Antigenc-ABL Tyr204
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SpecificityThis is a highly specific antibody against c-ABL Tyr204.
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Modification sPhosphorylation
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Modification site sTyr204
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ClonalityPolyclonal antibody
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Clone numberPolyclonal antibody
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Concentration1ug per 1ul
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SourceKLH conjugated synthetic phosphopeptide derived from human c-Abl isoform b around the phosphorylation site of Tyr204
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Gene ID number25
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Tested ApplicationsWB, IHC-P, IF(IHC-P)
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Recommended dilutionsWB(1:100-1000), IHC-P(1:100-500), IF(IHC-P)(1:50-200)
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Cross reactivityHuman, Mouse, Rat
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Cross reactive species detailsDue to limited amount of testing and knowledge, not every possible cross-reactivity is known.
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Background of the target antigenThe c Abl proto oncogene encodes a protein tyrosine kinase that is located in the cytoplasm and nucleus. In chronic myelogenous leukemia and in a subset of acute lymphoblastic leukemias, the c Abl proto oncogene undergoes a (9;22) chromosomal translocation producing a novel rearranged chromosome (the Philadelphia chromosome) As the result of the fusion of c Abl sequences from chromosome 9 to the Bcr gene on chromosome 22. The molecular consequence of this translocation is the generation of a chimeric Bcr/Abl mRNA encoding activated Abl protein tyrosine kinase.
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Purification methodThis antibody was purified via Protein A.
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Storage conditionsKeep the antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store at -20°C for up to 1 year.
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Synonym namesc-Ablphospho Y204; c-Ablphospho Tyr204; p-c-AblTyr204; Abelson Murine Leukemia Viral Oncogene Homolog 1; Abelson murine leukemia viral v abl oncogene homolog 1; Abl 1; ABL; Abl protein; Abl1; Bcr/c abl oncogene protein; JTK 7; JTK7; p150; Proto oncogene tyrosine protein kinase ABL1; Transformation gene oncogene ABL; v abl Abelson murine leukemia viral oncogene homolog 1; v abl; ABL1_HUMAN.
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PropertiesIf you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
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French translationanticorps
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Gene target
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Gene symbolABL1, MTTP
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Short nameAnti-c-ABL Tyr204
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TechniqueAntibody, antibodies against human proteins, antibodies for
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HostRabbit (Oryctolagus cuniculus)
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IsotypeImmunoglobulin G (IgG)
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Alternative namec-ABL(Tyr204) Polyclonal Antibody
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Alternative techniqueantibodies
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Gene info
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Identity
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Gene
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Long gene nameABL proto-oncogene 1, non-receptor tyrosine kinase
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Synonyms gene
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Synonyms gene name
- v-abl Abelson murine leukemia viral oncogene homolog 1
- c-abl oncogene 1, receptor tyrosine kinase
- c-abl oncogene 1, non-receptor tyrosine kinase
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Synonyms
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GenBank acession
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Locus
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Discovery year1986-01-01
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Abl family tyrosine kinases
- SH2 domain containing
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VEGA ID
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Locus Specific Databases
Gene info
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Identity
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Gene
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Long gene namemicrosomal triglyceride transfer protein
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Synonyms gene
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Synonyms gene name
- microsomal triglyceride transfer protein (large polypeptide, 88kD)
- microsomal triglyceride transfer protein (large polypeptide, 88kDa)
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Synonyms
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Locus
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Discovery year1994-12-07
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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VEGA ID
MeSH Data
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Name
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ConceptScope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
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Tree numbers
- E05.196.401.143
- E05.301.300.096
- E05.478.566.320.200
- E05.601.262
- E05.601.470.320.200
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Qualifiersethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data