EGF Recombinant Protein
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Catalog number40-586
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PricePlease ask
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Size0.1 mg, 0.5 mg
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About recombinant proteinEGF is a potent growth factor that stimulates the proliferation of various epidermal and epithelial cells. Additionally, EGF has been shown to inhibit gastric secretion, and to be involved in wound healing. EGF signals through a receptor known as c-erbB, which is a class I tyrosine kinase receptor. This receptor also binds with TGF-a and VGF (vaccinia virus growth factor). Recombinant human EGF is a 6.2 kDa globular protein containing 53 amino acid residues including 3 intramolecular disulfide-bonds.
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Other name of the recombinantURG, HOMG4, Pro-epidermal growth factor, Urogastrone, EGF
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Recombinant inE. coli
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SEQUENCENSDSECPLSH DGYCLHDGVC MYIEALDKYA CNCVVGYIGE RCQYRDLKWW ELR
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ActivityThe ED50 was determined by a cell proliferation assay using balb/c 3T3 cells is = 0.1 ng/mL, corresponding to a specific activity of = 1 x107 units/mg.
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Keep atThe lyophilized EGF recombinant protein is stable for at least 2 years from date of receipt at -20˚C. Reconstituted EGF is stable for at least 3 months when stored in working aliquots with a carrier protein at -20˚C. As with any protein, exposing EGF recombinant protein to repeated freeze / thaw cycles is not recommended. When working with proteins care should be taken to keep recombinant protein at a cool and stable temperature.
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Rec PROTEIN GI166362728
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Accession nrNP_001954.2
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PureityGreater than 95% by SDS-PAGE gel and HPLC analyses.
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AboutThis product is for research use only.
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Protein s originHuman
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VialLyophilized
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NCBI ID1950
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Gene nameepidermal growth factor
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SourceHomo sapiens
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UniprotP01133
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Additional sourceRecombinants or rec. proteins
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Grouprecombinants
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Gene target
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Gene symbolEGF
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Short nameEGF Recombinant Protein
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TechniqueRecombinant, E. coli recombinant proteins are genetic recombinations in Escherichia coli, supplied as white sterile powder lyopillized. proscience advises they will be reconstituted in a buffer soluion or culture medium for cell culture.
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Alternative nameepidermal growth factor Rec. Protein
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Alternative techniquerec
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Alternative to gene targetepidermal growth factor, HOMG4 and URG, EGF and IDBG-34100 and ENSG00000138798 and 1950, transmembrane receptor protein tyrosine kinase activator activity, Extracellular, Egf and IDBG-193432 and ENSMUSG00000028017 and 13645
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Gene info
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Identity
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Gene
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Long gene nameepidermal growth factor
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Synonyms gene name
- epidermal growth factor (beta-urogastrone)
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Synonyms name
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GenBank acession
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Locus
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Discovery year2001-06-22
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Entrez gene record
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VEGA ID
MeSH Data
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Name
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ConceptScope note: The initial culturing of cells derived directly from fresh TISSUES.
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Tree numbers
- E01.370.225.500.223.500
- E05.200.500.265.500
- E05.242.223.500
- E05.481.500.249.500
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Qualifiersethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data