C4B Antibody
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Catalog numberF40031-0.4ML
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PricePlease ask
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Size0.4 ml
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CategoryAntibody
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ConcentrationIn 1X PBS, pH 7.4, with 0.09% sodium azide
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FormAntigen affinity purified
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ConjugationUnconjugated
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ClonePolyclonal antibody
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Recognised antigenC4B
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Host animalRabbit (Oryctolagus cuniculus)
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ClonalityPolyclonal (rabbit origin)
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Species reactivityMouse (Mus musculus) ; Due to limited knowledge and inability to test the antibody against all known species, we cannot guarantee that no other cross reactivity can occur.
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Tested applicationsWB, ELISA
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Recommended dilutionsWestern blot: 1:1000
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NotesTitration of the C4B antibody may be required due to differences in protocols and secondary/substrate sensitivity.
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Intented useThis C4B antibodyis to be used only for research purposes and not for diagnostics..
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UniprotP0C0L4
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PurityAntigen affinity
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DescriptionThis gene encodes the basic form of complement factor 4, part of the classical activation pathway. The protein is expressed as a single chain precursor which is proteolytically cleaved into a trimer of alpha, beta, and gamma chains prior to secretion. The trimer provides a surface for interaction between the antigen-antibody complex and other complement components. The alpha chain may be cleaved to release C4 anaphylatoxin, a mediator of local inflammation. Deficiency of this protein is associated with systemic lupus erythematosus. This gene localizes to the major histocompatibility complex (MHC) class III region on chromosome 6. Varying haplotypes of this gene cluster exist, such that individuals may have 1, 2, or 3 copies of this gene. In addition, this gene exists as a long form and a short form due to the presence or absence of a 6.4 kb endogenous HERV-K retrovirus in intron 9.
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ImmunogenA portion of amino acids 655-684 from the human protein was used as the immunogen for this C4B antibody.
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StorageAliquot the C4B antibody and store frozen at -20 deg. Celcius or lower. Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity. Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized.
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PropertiesIf you buy Antibodies supplied by NJS poly they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
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French translationanticorps
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Gene target
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Gene symbolC4B-AS1, C4B, C4A
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Short nameAnti-C4B
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TechniqueAntibody, antibodies against human proteins, antibodies for
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IsotypeRabbit Ig
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Alternative nameAntibodies to C4B
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Alternative techniqueantibodies
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Alternative to gene targetcomplement component 4B (Chido blood group), C4B_2 and C4B1 and C4B12 and C4B2 and C4B3 and C4B5 and C4BD and C4F and CH and CO4 and CPAMD3, C4B and IDBG-301132 and ENSG00000224389 and 100293534,721, carbohydrate binding, Extracellular
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Gene info
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Identity
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Gene
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Long gene nameC4B antisense RNA 1
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Synonyms gene name
- C4B antisense RNA 1 (non-protein coding)
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Locus
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Discovery year2011-04-21
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Classification
- Antisense RNAs
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VEGA ID
Gene info
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Identity
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Gene
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Long gene namecomplement C4B (Chido blood group)
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Synonyms gene name
- complement component 4B
- complement component 4B (Chido blood group)
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Synonyms
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GenBank acession
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Locus
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Discovery year2001-06-22
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Entrez gene record
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RefSeq identity
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Classification
- C3 and PZP like, alpha-2-macroglobulin domain containing
- Blood group antigens
- Complement system activation components
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VEGA ID
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Locus Specific Databases
Gene info
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Identity
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Gene
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Long gene namecomplement C4A (Rodgers blood group)
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Synonyms gene name
- complement component 4A
- complement component 4A (Rodgers blood group)
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Synonyms
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GenBank acession
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Locus
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Discovery year2001-06-22
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Entrez gene record
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RefSeq identity
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Classification
- C3 and PZP like, alpha-2-macroglobulin domain containing
- Blood group antigens
- Complement system activation components
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VEGA ID
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Locus Specific Databases
MeSH Data
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Name
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ConceptScope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
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Tree numbers
- E05.196.401.143
- E05.301.300.096
- E05.478.566.320.200
- E05.601.262
- E05.601.470.320.200
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Qualifiersethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data