Clasto-lactacystin (Omuralide)

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Stock availability

In Stock
Cas number

154226-60-5
Chemical s molecular weight

213.23
Chemical s main applications

A cell permeable, irreversible proteasome inhibitor. It is 20-fold more potent than Lactacystin. Lactacytstin spontaneously converts to clasto-lactacystin in biological systems. Clasto-lactacystin is the only cell permeable form of lactacystin. Induces neurite growth and inhibits cell cycle progression similar to lactacytin.
Chemical s category

Inhibitors
Other name

(1R,4R,5S)-1-[(1S)-1-Hydroxy-2-methylpropyl]-4-methyl-6-oxa-2-azabicyclo[3.2.0]heptane-3,7-dione; Clasto-lactacystin β-Lactone; Omuralide
Chemical s formula

C10H15NO4
Physical properties

White Solid
Melting temperature

186-187°C
Boiling temperature

No Data Available
Chemical s soluble in

DMF, Ethanol, Hot Ethyl Acetate, Methanol, Pyridine
Stability conditions

No Data Available
Storage

-20°C Freezer
Chemical s specifications