TLR8 (TAntibody (Clone 44B05)

• Catalog number
  3558-100
• Price
  Please ask
• Size
  100 µl

• Antibody Target
  TLR8
• Target Alternative Name
  LR8 , Anti-TLR8 , CD288 , CD 288 , mgC119599 , # mgC119600
• Antibody Type
  Monoclonal
• Clone
  44B05
• Species Reactivities
  Human
• Immunogen Sequence
  Recombinant human TLR8
• Accession
  NP_619542
• Gene Id
  51311
• Appearance
  Colorless liquid
• Form
  Liquid
• Concentration
  1.0 mg/ml
• Formulation
  100 µl (1 mg/ml) Protein G purified mouse anti-TLR8 monoclonal antibody in phosphate buffered saline (PBS), pH 7.2, containing 50% glycerol, 1% BSA, 0.02% thimerosal.
• Purification
  Affinity purified
• Application
  Western blot, Flow cytometry
• Application And Usages
  Western blotting (1:200-1000 dilutions) and FACS analysis. Ramos cell lysate can be used as a positive control and a 120 kDa band is detected in Western blotting. For FACS analysis, we recommend 1-4 ml per million cells. However, the optimal conditions should be determined individually.
• Description
  The Toll-like receptor (TLR) family of proteins are characterized by a highly conserved Toll homology (TH) domain, which is essential for Toll-induced signal transduction. TLR1 contains an extracellular domain consisting of several leucine-rich regions along with a single cytoplasmic Toll/IL-1R-like domain. TLR2 and TLR4 are activated in response to lipopolysacchride (LPS) stimulation, which results in the activation and translocation of NFkB and sμggests that these receptors are involved in mediating inflammatory responses. TLR6 is highly homologous to TLR1, and like other members of TLR family, it induces NFkB signaling upon activation. TLR8 gene contains three exons, two of which have coding function. Expression of TLR receptors is highest in peripheral blood leukocytes, macrophages, and monocytes.
• Storage Condition
  -20 °C
• Shipping Condition
  gel pack
• Shelf Life
  12 months
• Usage
  For Research Use Only! Not to be used in humans.
• Handling
  The antibody solution should be gently mixed before use.
• Western Blot Verified
  Verified
• Immunocytochemistry Verified
  Not Verified
• Immunofluorescence Verified
  Not Verified
• Immunoprecipitation Verified
  Not Verified
• ELISA Verified
  Not Verified
• ChIP Verified
  Not Verified
• Flow Cytometry Verified
  Not Verified
• Data Sheet Link

• Gene target
  TLR8   TAntibody   44B05  
• Gene symbol
  TLR8-AS1, TLR8
• Short name
  TLR8 (TAntibody (Clone 44B05)
• Isotype
  Mouse IgG1
• Alternative name
  toll-like receptor 8 (TAntibody (clonality 44B05)
• Alternative to gene target
  toll-like receptor 8, TLR8 and IDBG-44288 and ENSG00000101916 and 51311, drug binding, Plasma membranes, Tlr8 and IDBG-185523 and ENSMUSG00000040522 and 170744
• Clone name
  44B05

Gene info

• Identity
  HGNC:40720
• Gene
  TLR8-AS1
• Long gene name
  TLR8 antisense RNA 1
• Synonyms gene name
  • TLR8 antisense RNA 1 (non-protein coding)
• Locus
  Xp22.2
• Discovery year
  2011-07-29
• Entrez gene record
  349408
• Classification
  • Antisense RNAs
• VEGA ID
  OTTHUMG00000021142

Gene info

• Identity
  HGNC:15632
• Gene
  TLR8
• Long gene name
  toll like receptor 8
• Synonyms gene name
  • toll-like receptor 8
• Synonyms
  • CD288
  • hTLR8
• GenBank acession
  • AF246971
• Locus
  Xp22.2
• Discovery year
  2001-04-27
• Entrez gene record
  51311
• Pubmed identfication
  • 11022119
• RefSeq identity
  • NM_016610
• Classification
  • Toll like receptors
  • CD molecules
• VEGA ID
  OTTHUMG00000021145
• Locus Specific Databases
  • Global Variome shared LOVD

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

Product images

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