TLR8 Antibody

• Catalog number
  F44380-0.08ML
• Price
  Please ask
• Size
  0.08 ml

• Category
  Antibody
• Concentration
  In 1X PBS pH 7.4 with 0.09% sodium azide
• Form
  Antigen affinity purified
• Conjugation
  Unconjugated
• Clone
  Polyclonal antibody
• Recognised antigen
  TLR8
• Host animal
  Rabbit (Oryctolagus cuniculus)
• Clonality
  Polyclonal (rabbit origin)
• Species reactivity
  Human (Homo sapiens), Mouse (Mus musculus) ; Due to limited knowledge and inability to test the antibody against all known species, we cannot guarantee that no other cross reactivity can occur.
• Tested applications
  WB, IHC, ELISA
• Recommended dilutions
  Western blot: 1:1000,IHC (Paraffin): 1:10-1:50
• Notes
  Titration of the TLR8 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
• Intented use
  This TLR8 antibodyis to be used only for research purposes and not for diagnostics..
• Uniprot
  P58682
• Purity
  Antigen affinity
• Description
  TLR8 is a member of the Toll-like receptor (TLR) family which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. They recognize pathogen-associated molecular patterns (PAMPs) that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity. The various TLRs exhibit different patterns of expression. TLR8 is predominantly expressed in lung and peripheral blood leukocytes, and lies in close proximity to another family member, TLR7, on chromosome X.
• Immunogen
  A portion of amino acids 957-987 from the mouse protein was used as the immunogen for this TLR8 antibody.
• Storage
  Aliquot the TLR8 antibody and store frozen at -20 deg. Celcius or lower. Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity. Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized.
• Properties
  If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• French translation
  anticorps

• Gene target
  TLR8  
• Gene symbol
  TLR8-AS1, TLR8
• Short name
  Anti-TLR8
• Technique
  Antibody, antibodies against human proteins, antibodies for
• Isotype
  Rabbit Ig
• Alternative name
  Antibodies to TLR8
• Alternative technique
  antibodies
• Alternative to gene target
  toll-like receptor 8, TLR8 and IDBG-44288 and ENSG00000101916 and 51311, drug binding, Plasma membranes, Tlr8 and IDBG-185523 and ENSMUSG00000040522 and 170744

Gene info

• Identity
  HGNC:40720
• Gene
  TLR8-AS1
• Long gene name
  TLR8 antisense RNA 1
• Synonyms gene name
  • TLR8 antisense RNA 1 (non-protein coding)
• Locus
  Xp22.2
• Discovery year
  2011-07-29
• Entrez gene record
  349408
• Classification
  • Antisense RNAs
• VEGA ID
  OTTHUMG00000021142

Gene info

• Identity
  HGNC:15632
• Gene
  TLR8
• Long gene name
  toll like receptor 8
• Synonyms gene name
  • toll-like receptor 8
• Synonyms
  • CD288
  • hTLR8
• GenBank acession
  • AF246971
• Locus
  Xp22.2
• Discovery year
  2001-04-27
• Entrez gene record
  51311
• Pubmed identfication
  • 11022119
• RefSeq identity
  • NM_016610
• Classification
  • Toll like receptors
  • CD molecules
• VEGA ID
  OTTHUMG00000021145
• Locus Specific Databases
  • Global Variome shared LOVD

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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