Anti-SP-C Propeptide (Polyclonal), ALEXA Fluor 594
-
Catalog numberGENTObs-10378R-A594
-
PricePlease ask
-
Size100 microliters
-
-
TypeConjugated Primary Antibody
-
Conjugated withALEXA FLUOR® 594
-
Host organismRabbit (Oryctolagus cuniculus)
-
Target Protein PeptideSP-C Propeptide
-
SpecificityThis antibody reacts specifically with SP-C Propeptide
-
ModificationNo modification has been applied to this antibody
-
Modification siteNone
-
ClonalityPolyclonal Antibody
-
ClonePolyclonal Antibodies
-
Concentration1ug per 1ul
-
Subcellular locationsN/A
-
Antigen SourceKLH conjugated synthetic peptide derived from human SP-C Propeptide
-
Gene ID6440
-
Swiss ProtN/A
-
ApplicationsIF(IHC-P)
-
Applications with corresponding dilutionsIF(IHC-P)(1:50-200)
-
Cross reactive speciesHuman (Homo sapiens), Mouse (Mus musculus), Rat (Rattus norvegicus)
-
Cross Reactive Species detailsNo significant cross reactivity has been observed for this antibody for the tested species. However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species.
-
Background informationThis gene encodes the pulmonary-associated surfactant protein C (SPC), an extremely hydrophobic surfactant protein essential for lung function and homeostasis after birth. Pulmonary surfactant is a surface-active lipoprotein complex composed of 90% lipids and 10% proteins which include plasma proteins and apolipoproteins SPA, SPB, SPC and SPD. The surfactant is secreted by the alveolar cells of the lung and maintains the stability of pulmonary tissue by reducing the surface tension of fluids that coat the lung. Multiple mutations in this gene have been identified, which cause pulmonary surfactant metabolism dysfunction type 2, also called pulmonary alveolar proteinosis due to surfactant protein C deficiency, and are associated with interstitial lung disease in older infants, children, and adults. Alternatively spliced transcript variants encoding different protein isoforms have been identified.
-
Purification methodPurified by Protein A.
-
StorageWater buffered solution containing 100ug/ml BSA, 50% glycerol and 0.09% sodium azide. Store at 4°C for 12 months.
-
Excitation emission590nm/617nm
-
SynonymsPSP C; PSPC; Pulmonary surfactant apoprotein 2; pulmonary surfactant apoprotein PSP C; pulmonary surfactant associated protein C; pulmonary surfactant associated proteolipid SPL pVal; Pulmonary surfactant associated proteolipid SPLVal; SFTP 2; SFTP2; SFTPC; SFTPC surfactant pulmonary associated protein C; SP 5; SP C; SP5; SPC; surfactant associated protein pulmonary 2; Surfactant protein c; Surfactant pulmonary associated protein C; PSPC_HUMAN.
-
Also known asSP-C Propeptide Polyclonal Antibody
-
Other nameAnti-SP-C Propeptide Polyclonal
-
AdvisoryAvoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody, thus reducing its reactivity, specificity and sensitivity. For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube. Prior to use briefly centrifuge the vial to gather all the solution on the bottom.
-
PropertiesFor facs or microscopy Alexa 1 conjugate.
-
ConjugationAlexa Fluor, ALEXA FLUOR® 594
-
ConjugatedAlexa conjugate 1
-
DescriptionThis antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided. Antibody for research use.
-
GroupPolyclonals and antibodies
-
AboutPolyclonals can be used for Western blot, immunohistochemistry on frozen slices or parrafin fixed tissues. The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera.
-
Gene target
-
Gene symbolSFTPC, SFTPA1, UCN3, SPATA1, SPESP1, REXO5, SFTA2, SMC4, SFTPA2, SFTPB
-
Short nameAnti-SP-C Propeptide
-
TechniquePolyclonal, anti-, anti, antibody to, antibodies, Polyclonal antibodies (pAbs) are mostly rabbit or goat antibodies that are secreted by different B cells, whereas monoclonal antibodies come from a single N cell lineage. Pabs are a collection of immunoglobulin molecules that react against a specific antigen, each identifying a different epitope.
-
IsotypeImmunoglobulin G (IgG)
-
LabelALEXA FLUOR 594
-
Alternative nameSP-C Propeptide Polyclonal Antibody, ALEXA FLUOR® 594 Conjugated
-
Alternative techniquepolyclonals, antibodies
-
Gene info
-
Identity
-
Gene
-
Long gene namesurfactant protein C
-
Synonyms gene
-
Synonyms gene name
- surfactant, pulmonary-associated protein C
-
Synonyms
-
Synonyms name
-
Locus
-
Discovery year1988-05-11
-
Entrez gene record
-
Pubmed identfication
-
RefSeq identity
-
Classification
- BRICHOS domain containing
-
VEGA ID
Gene info
-
Identity
-
Gene
-
Long gene namesurfactant protein A1
-
Synonyms gene
-
Synonyms gene name
- surfactant, pulmonary-associated protein A1
-
Synonyms
-
Synonyms name
-
GenBank acession
-
Locus
-
Discovery year2001-06-22
-
Entrez gene record
-
RefSeq identity
-
Classification
- Collectins
- C-type lectin domain containing
-
VEGA ID
Gene info
-
Identity
-
Gene
-
Long gene nameurocortin 3
-
Synonyms
-
Synonyms name
-
GenBank acession
-
Locus
-
Discovery year2003-11-06
-
Entrez gene record
-
Pubmed identfication
-
RefSeq identity
-
Classification
- Neuropeptides
-
VEGA ID
Gene info
-
Identity
-
Gene
-
Long gene namespermatogenesis associated 1
-
Synonyms
-
GenBank acession
-
Locus
-
Discovery year2001-03-01
-
Entrez gene record
-
RefSeq identity
-
VEGA ID
Gene info
-
Identity
-
Gene
-
Long gene namesperm equatorial segment protein 1
-
Synonyms
-
GenBank acession
-
Locus
-
Discovery year2001-04-24
-
Entrez gene record
-
Pubmed identfication
-
RefSeq identity
-
VEGA ID
Gene info
-
Identity
-
Gene
-
Long gene nameRNA exonuclease 5
-
Synonyms
-
GenBank acession
-
Locus
-
Discovery year2017-03-29
-
Entrez gene record
-
Pubmed identfication
-
RefSeq identity
Gene info
-
Identity
-
Gene
-
Long gene namesurfactant associated 2
-
Synonyms gene
-
Synonyms gene name
- surfactant associated protein G
-
Synonyms
-
GenBank acession
-
Locus
-
Discovery year2002-05-01
-
Entrez gene record
-
Pubmed identfication
-
RefSeq identity
-
VEGA ID
Gene info
-
Identity
-
Gene
-
Long gene namestructural maintenance of chromosomes 4
-
Synonyms gene
-
Synonyms gene name
- SMC4 (structural maintenance of chromosomes 4, yeast)-like 1
- SMC4 structural maintenance of chromosomes 4-like 1 (yeast)
-
Synonyms
-
GenBank acession
-
Locus
-
Discovery year2001-02-22
-
Entrez gene record
-
Pubmed identfication
-
Classification
- Structural maintenance of chromosomes proteins
- Condensin I subunits
- Condensin II subunits
- MicroRNA protein coding host genes
-
VEGA ID
Gene info
-
Identity
-
Gene
-
Long gene namesurfactant protein A2
-
Synonyms gene name
- surfactant, pulmonary-associated protein A2
-
Synonyms
-
Synonyms name
-
Locus
-
Discovery year1997-04-16
-
Entrez gene record
-
RefSeq identity
-
Classification
- C-type lectin domain containing
- Collectins
-
VEGA ID
Gene info
-
Identity
-
Gene
-
Long gene namesurfactant protein B
-
Synonyms gene
-
Synonyms gene name
- surfactant, pulmonary-associated protein B
-
Synonyms
-
GenBank acession
-
Locus
-
Discovery year1988-07-06
-
Entrez gene record
-
Pubmed identfication
-
RefSeq identity
-
VEGA ID
MeSH Data
-
Name
-
ConceptScope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
-
Tree numbers
- E05.196.401.143
- E05.301.300.096
- E05.478.566.320.200
- E05.601.262
- E05.601.470.320.200
-
Qualifiersethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data