SP-C Propeptide Antibody, ALEXA FLUOR 647

• Catalog number
  bs-10378R-A647
• Price
  Please ask
• Size
  100ul

• Long name
  SP-C Propeptide Polyclonal Antibody, ALEXA FLUOR 647 Conjugated
• Also known as
  Anti-SP-C Propeptide PAb ALEXA FLUOR 647
• Category
  Conjugated Primary Antibodies
• Conjugated with
  ALEXA FLUOR® 647
• Host Organism
  Rabbit (Oryctolagus cuniculus)
• Target Antigen
  SP-C Propeptide
• Specificity
  This is a highly specific antibody against SP-C Propeptide.
• Modification
  Unmodified
• Modification Site
  None
• Clonality
  Polyclonal
• Clone
  Polyclonal antibody
• Concentration
  1ug per 1ul
• Source
  This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human SP-C Propeptide
• Gene ID Number
  6440
• Tested applications
  IF(IHC-P)
• Recommended dilutions
  IF(IHC-P)(1:50-200)
• Crossreactivity
  Human, Mouse, Rat
• Cross reactive species details
  Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.
• Background of the antigen
  This gene encodes the pulmonary-associated surfactant protein C (SPC), an extremely hydrophobic surfactant protein essential for lung function and homeostasis after birth. Pulmonary surfactant is a surface-active lipoprotein complex composed of 90% lipids and 10% proteins which include plasma proteins and apolipoproteins SPA, SPB, SPC and SPD. The surfactant is secreted by the alveolar cells of the lung and maintains the stability of pulmonary tissue by reducing the surface tension of fluids that coat the lung. Multiple mutations in this gene have been identified, which cause pulmonary surfactant metabolism dysfunction type 2, also called pulmonary alveolar proteinosis due to surfactant protein C deficiency, and are associated with interstitial lung disease in older infants, children, and adults. Alternatively spliced transcript variants encoding different protein isoforms have been identified.
• Purification
  Purified by Protein A.
• Storage conditions
  Store this antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Keep refrigerated at 2 to 8 degrees Celcius for up to one year.
• Excitation emission
  650nm/665nm
• Synonyms
  PSP C; PSPC; Pulmonary surfactant apoprotein 2; pulmonary surfactant apoprotein PSP C; pulmonary surfactant associated protein C; pulmonary surfactant associated proteolipid SPL pVal; Pulmonary surfactant associated proteolipid SPLVal; SFTP 2; SFTP2; SFTPC; SFTPC surfactant pulmonary associated protein C; SP 5; SP C; SP5; SPC; surfactant associated protein pulmonary 2; Surfactant protein c; Surfactant pulmonary associated protein C; PSPC_HUMAN.
• Properties
  For facs or microscopy Alexa 1 conjugate. Alexa Fluor 633 is a practical alternative to APC as well as Cy5. Bioss Primary Conjugated Antibodies. ALEXA FLUOR made this Alexa Fluor 633 conjugate that can be used in multi-color flow cytometry with instruments equipped with a second red laser or red diode. It is detected in the FL4 detector of the core's upgraded 2-laser FACScans. Like other Alexa Fluor dyes, the Anti-SP-C Propeptide exhibits uncommon photo stability, making it an ideal choice for fluorescent microscopy. If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies. ALEXA FLUOR they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• Conjugation
  Alexa Fluor, ALEXA FLUOR 647
• French translation
  anticorps

• Gene target
  SP-C   Propeptide  
• Gene symbol
  SFTPC, SFTPA1, UCN3, SPATA1, SPESP1, REXO5, SFTA2, SMC4, SFTPA2, SFTPB
• Short name
  Anti-SP-C Propeptide
• Technique
  Antibody, antibodies against human proteins, antibodies for
• Isotype
  Immunoglobulin G (IgG)
• Label
  ALEXA FLUOR 647
• Alternative name
  SP-C Propeptide Polyclonal Antibody, ALEXA FLUOR 647
• Alternative technique
  antibodies

Gene info

• Identity
  HGNC:10802
• Gene
  SFTPC
• Long gene name
  surfactant protein C
• Synonyms gene
  • SFTP2
• Synonyms gene name
  • surfactant, pulmonary-associated protein C
• Synonyms
  • SP-C
  • PSP-C
  • SMDP2
  • BRICD6
• Synonyms name
  • BRICHOS domain containing 6
• Locus
  8p21.3
• Discovery year
  1988-05-11
• Entrez gene record
  6440
• Pubmed identfication
  • 1859376
  • 16709565
• RefSeq identity
  • NM_003018
• Classification
  • BRICHOS domain containing
• VEGA ID
  OTTHUMG00000163775

Gene info

• Identity
  HGNC:10798
• Gene
  SFTPA1
• Long gene name
  surfactant protein A1
• Synonyms gene
  • SFTP1
• Synonyms gene name
  • surfactant, pulmonary-associated protein A1
• Synonyms
  • SP-A
  • SP-A1
  • COLEC4
• Synonyms name
  • surfactant, pulmonary-associated protein A1A
• GenBank acession
  • BC026229
• Locus
  10q22.3
• Discovery year
  2001-06-22
• Entrez gene record
  653509
• RefSeq identity
  • NM_005411
• Classification
  • Collectins
  • C-type lectin domain containing
• VEGA ID
  OTTHUMG00000018565

Gene info

• Identity
  HGNC:17781
• Gene
  UCN3
• Long gene name
  urocortin 3
• Synonyms
  • UCNIII
  • SPC
• Synonyms name
  • stresscopin
  • prepro-urocortin 3
• GenBank acession
  • AF361943
• Locus
  10p15.1
• Discovery year
  2003-11-06
• Entrez gene record
  114131
• Pubmed identfication
  • 11416224
• RefSeq identity
  • NM_053049
• Classification
  • Neuropeptides
• VEGA ID
  OTTHUMG00000017594

Gene info

• Identity
  HGNC:14682
• Gene
  SPATA1
• Long gene name
  spermatogenesis associated 1
• Synonyms
  • SP-2
• GenBank acession
  • AF306347
• Locus
  1p22.3
• Discovery year
  2001-03-01
• Entrez gene record
  100505741
• RefSeq identity
  • NM_022354
• VEGA ID
  OTTHUMG00000009924

Gene info

• Identity
  HGNC:15570
• Gene
  SPESP1
• Long gene name
  sperm equatorial segment protein 1
• Synonyms
  • SP-ESP
• GenBank acession
  • AF275321
• Locus
  15q23
• Discovery year
  2001-04-24
• Entrez gene record
  246777
• Pubmed identfication
  • 12773409
• RefSeq identity
  • NM_145658
• VEGA ID
  OTTHUMG00000133321

Gene info

• Identity
  HGNC:24661
• Gene
  REXO5
• Long gene name
  RNA exonuclease 5
• Synonyms
  • NEF-sp
• GenBank acession
  • AF332193
• Locus
  16p12.3
• Discovery year
  2017-03-29
• Entrez gene record
  81691
• Pubmed identfication
  • 28539487
  • 29045842
• RefSeq identity
  • NM_030941

Gene info

• Identity
  HGNC:18386
• Gene
  SFTA2
• Long gene name
  surfactant associated 2
• Synonyms gene
  • SFTPG
• Synonyms gene name
  • surfactant associated protein G
• Synonyms
  • SP-G
• GenBank acession
  • AY102070
• Locus
  6p21.33
• Discovery year
  2002-05-01
• Entrez gene record
  389376
• Pubmed identfication
  • 22768197
  • 23094088
• RefSeq identity
  • NM_205854
• VEGA ID
  OTTHUMG00000031183

Gene info

• Identity
  HGNC:14013
• Gene
  SMC4
• Long gene name
  structural maintenance of chromosomes 4
• Synonyms gene
  • SMC4L1
• Synonyms gene name
  • SMC4 (structural maintenance of chromosomes 4, yeast)-like 1
  • SMC4 structural maintenance of chromosomes 4-like 1 (yeast)
• Synonyms
  • hCAP-C
  • CAP-C
• GenBank acession
  • AF092564
• Locus
  3q25.33
• Discovery year
  2001-02-22
• Entrez gene record
  10051
• Pubmed identfication
  • 9789013
  • 10319587
• Classification
  • Structural maintenance of chromosomes proteins
  • Condensin I subunits
  • Condensin II subunits
  • MicroRNA protein coding host genes
• VEGA ID
  OTTHUMG00000159006

Gene info

• Identity
  HGNC:10799
• Gene
  SFTPA2
• Long gene name
  surfactant protein A2
• Synonyms gene name
  • surfactant, pulmonary-associated protein A2
• Synonyms
  • SP-A2
  • COLEC5
• Synonyms name
  • surfactant, pulmonary-associated protein A2A
• Locus
  10q22.3
• Discovery year
  1997-04-16
• Entrez gene record
  729238
• RefSeq identity
  • NM_001098668
• Classification
  • C-type lectin domain containing
  • Collectins
• VEGA ID
  OTTHUMG00000018566

Gene info

• Identity
  HGNC:10801
• Gene
  SFTPB
• Long gene name
  surfactant protein B
• Synonyms gene
  • SFTP3
• Synonyms gene name
  • surfactant, pulmonary-associated protein B
• Synonyms
  • SP-B
• GenBank acession
  • J02761
• Locus
  2p11.2
• Discovery year
  1988-07-06
• Entrez gene record
  6439
• Pubmed identfication
  • 2924687
  • 1346779
• RefSeq identity
  • NM_198843
• VEGA ID
  OTTHUMG00000130181

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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