anti-Caspase-9 Antibody
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Catalog number2073
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PricePlease ask
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Size0.02 mg, 0.1 mg
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Gene infoCaspase-9 Antibody: Apoptosis is related to many diseases and induced by a family of cell death receptors and their ligands. Cell death signals are transduced by death domain containing adapter molecules and members of the caspase family of proteases. A novel member in the caspase family was recently identified and designated ICE-LAP6, Mch6, and Apaf-3. Caspase-9 and Apaf-1 bind to each other, which leads to caspase-9 activation. Caspase-9 is also activated by granzyme B and CPP32. Activated caspase-9 cleaves and activates caspase-3 that is one of the key proteases, being responsible for the proteolytic cleavage of many key proteins in apoptosis. Caspase-9 play a central role in cell death induced by a wide variety of apoptosis activators including TNFa;, TRAIL, anti-CD-95, FADD, and TRADD. Caspase-9 is expressed in a variety of human tissues.
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Gene namesCaspase-9 Antibody: MCH6, APAF3, APAF-3, PPP1R56, ICE-LAP6, MCH6, Caspase-9, Apoptotic protease Mch-6, CASP-9
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Antibodie s labelunlabelled serum
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PurityCaspase-9 Antibody is affinity chromatography purified via peptide column.
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Ab raised inRabbit
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TypePolyclonal
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ImmunoglobulinIgG
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Spicific toCaspase-9 antibody is predicted to have no cross reactivity to other members in the caspase family.
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AntigenCaspase-9 antibody was made against a 20 amino acid peptide near the center of human Caspase-9.
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Immuno applicationELISA, Western Blot, immuno-cyto-chemistry, immuno fluorescence, immuno precipitation
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Antibody adviceCaspase-9 antibody can be used for detection of caspase-9 by Western blot at 1 ug/mL. Antibody can also be used for immunocytochemistry starting at 2 ug/mL. For immunofluorescence start at 20 ug/mL.
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Suspention pH azideCaspase-9 Antibody is supplied in PBS containing 0.02% sodium azide.
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Keep atCaspase-9 antibody can be stored at 4 grades C for three months and -20 grades C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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Works withHuman
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Omim nr28558771
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Ncbi nrP55211
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KDaPredicted: 46 kDa Observed: 45 kDa
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Vial with antibodyin solution
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Quantity per ml1 mg/mL
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NCBI GENE nr842
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GENE symbolCASP9
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Antigene namecaspase 9, apoptosis-related cysteine peptidase
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SourceHomo sapiens
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Protein nrP55211
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DescriptionThis antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided. Antibody for research use. Human and some mouse caspases are active in apoptosis and cell death and even in necrosis and inflammation. CASP Gene and orthologous enzymes have been identifies successfully in the signal transduction cascade and pathways.
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PropertiesIf you buy Antibodies supplied by proscience they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
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French translationanticorps
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Gene target
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Gene symbolCARD9, CASP9, CARD19
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Short nameanti-Caspase-9 Antibody
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TechniqueAntibody, anti-, anti, antibody to, antibodies, antibodies against human proteins, antibodies for
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Alternative nameAntibody toCasp-9 (antibody to-)
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Alternative techniqueantibodies
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Gene info
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Identity
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Gene
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Long gene namecaspase recruitment domain family member 9
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Synonyms gene name
- caspase recruitment domain family, member 9
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GenBank acession
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Locus
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Discovery year2001-08-13
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Caspase recruitment domain containing
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VEGA ID
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Locus Specific Databases
Gene info
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Identity
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Gene
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Long gene namecaspase 9
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Synonyms gene name
- caspase 9, apoptosis-related cysteine protease
- caspase 9, apoptosis-related cysteine peptidase
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Synonyms
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Synonyms name
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GenBank acession
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Locus
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Discovery year1996-11-11
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Caspases
- Apoptosome
- Caspase recruitment domain containing
- Protein phosphatase 1 regulatory subunits
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VEGA ID
Gene info
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Identity
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Gene
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Long gene namecaspase recruitment domain family member 19
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Synonyms gene
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Synonyms gene name
- chromosome 9 open reading frame 89
- caspase recruitment domain family, member 19
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Synonyms
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Synonyms name
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GenBank acession
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Locus
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Discovery year2004-02-19
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Caspase recruitment domain containing
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VEGA ID
MeSH Data
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Name
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ConceptScope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
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Tree numbers
- E05.196.401.143
- E05.301.300.096
- E05.478.566.320.200
- E05.601.262
- E05.601.470.320.200
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Qualifiersethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data