anti-Caspase-2 Antibody

• Catalog number
  3447
• Price
  Please ask
• Size
  0.02 mg, 0.1 mg

• Gene info
  Caspase-2 Antibody: Caspases are a family of cysteine proteases that can be divided into the apoptotic and inflammatory caspase subfamilies. Unlike the apoptotic caspases, members of the inflammatory subfamily are generally not involved in cell death but are associated with the immune response to microbial pathogens. Members of this subfamily include caspase-1, -4, -5, and -12 and can activate proinflammatory cytokines such as IL-1β and IL-18. Although phylogenetically similar to this subfamily, Caspase-2 is thought to be involved in stress-induced apoptosis. Caspase-2 has two major isoforms; overexpression on the long form results in apoptosis while that of the short form suppresses cell death.
• Gene names
  Caspase-2 Antibody: ICH1, NEDD2, CASP-2, NEDD-2, PPP1R57, ICH1, Caspase-2, Neural precursor cell expressed developmentally down-regulated protein 2
• Antibodie s label
  unlabelled serum
• Purity
  Caspase-2 Antibody is affinity chromatography purified via peptide column.
• Ab raised in
  Rabbit
• Type
  Polyclonal
• Immunoglobulin
  IgG
• Spicific to
  Depending on cell lines or tissues used, other cleavage products may be observed.
• Antigen
  Caspase-2 antibody was made against a 16 amino acid synthetic peptide from the amino-terminus of human Caspase-2.
• Immuno application
  ELISA, Western Blot, immuno-cyto-chemistry
• Antibody advice
  Caspase-2 antibody can be used for the detection of caspase-2 by Western blot at 0.5 to 2 ug/mL. Antibody can also be used for immunocytochemistry starting at 2 ug/mL.
• Suspention pH azide
  Caspase-2 Antibody is supplied in PBS containing 0.02% sodium azide.
• Keep at
  Caspase-2 antibody can be stored at 4 grades C for three months and -20 grades C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
• Works with
  Human, Mouse
• Omim nr
  83300977
• Ncbi nr
  P42575
• Vial with antibody
  in solution
• Quantity per ml
  1 mg/mL
• NCBI GENE nr
  835
• GENE symbol
  CASP2
• Antigene name
  caspase 2, apoptosis-related cysteine peptidase
• Source
  Homo sapiens
• Protein nr
  P42575
• Picture
• Pdf tech file
• More antibodies
• Description
  This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided. Antibody for research use. Human and some mouse caspases are active in apoptosis and cell death and even in necrosis and inflammation. CASP Gene and orthologous enzymes have been identifies successfully in the signal transduction cascade and pathways.
• Properties
  If you buy Antibodies supplied by proscience they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• French translation
  anticorps

• Gene target
  Caspase-2  
• Gene symbol
  CASP4, CASP1P2, CASP10
• Short name
  anti-Caspase-2 Antibody
• Technique
  Antibody, anti-, anti, antibody to, antibodies, antibodies against human proteins, antibodies for
• Alternative name
  Antibody toCasp-2 (antibody to-)
• Alternative technique
  antibodies

Gene info

• Identity
  HGNC:1505
• Gene
  CASP4
• Long gene name
  caspase 4
• Synonyms gene name
  • caspase 4, apoptosis-related cysteine protease
  • caspase 4, apoptosis-related cysteine peptidase
• Synonyms
  • ICE(rel)II
  • ICH-2
  • TX
• GenBank acession
  • U25804
• Locus
  11q22.3
• Discovery year
  1996-07-22
• Entrez gene record
  837
• Pubmed identfication
  • 7797510
  • 9250871
• RefSeq identity
  • NM_001225
• Classification
  • Caspases
  • Caspase recruitment domain containing
• VEGA ID
  OTTHUMG00000166078

Gene info

• Identity
  HGNC:43776
• Gene
  CASP1P2
• Long gene name
  caspase 1 pseudogene 2
• Synonyms gene name
  • caspase 1, apoptosis-related cysteine peptidase pseudogene 2
• Locus
  11q22.3
• Discovery year
  2012-02-24
• Entrez gene record
  440067
• RefSeq identity
  • NR_131905
• VEGA ID
  OTTHUMG00000166162

Gene info

• Identity
  HGNC:1500
• Gene
  CASP10
• Long gene name
  caspase 10
• Synonyms gene name
  • caspase 10, apoptosis-related cysteine protease
  • caspase 10, apoptosis-related cysteine peptidase
• Synonyms
  • MCH4
  • FLICE-2
• Synonyms name
  • FAS-associated death domain protein interleukin-1B-converting enzyme 2
• GenBank acession
  • U60519
• Locus
  2q33.1
• Discovery year
  1997-04-21
• Entrez gene record
  843
• Pubmed identfication
  • 8755496
• RefSeq identity
  • NM_032977
• Classification
  • Caspases
  • Death effector domain containing
  • Death inducing signaling complex
• VEGA ID
  OTTHUMG00000132818
• Locus Specific Databases
  • CASP10base: Mutation registry for Autoimmune lymphoproliferative syndrome, type II (ALPS2)
  • LRG_33

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

Similar products