Anti-Calcium Sensing Receptor, ALEXA Fluor 594
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Catalog numberGENTObs-8524R-A594
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PricePlease ask
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Size100 microliters
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TypeConjugated Primary Antibody
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Conjugated withALEXA FLUOR® 594
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Host organismRabbit (Oryctolagus cuniculus)
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Target Protein PeptideCalcium Sensing Receptor
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SpecificityThis antibody reacts specifically with Calcium Sensing Receptor
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ModificationNo modification has been applied to this antibody
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Modification siteNone
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ClonalityPolyclonal Antibody
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ClonePolyclonal Antibodies
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Concentration1ug per 1ul
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Subcellular locationsExtracellular
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Antigen SourceKLH conjugated synthetic peptide derived from human Calcium Sensing Receptor/CaSR
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Gene ID846
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Swiss ProtP41180
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ApplicationsIF(IHC-P)
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Applications with corresponding dilutionsIF(IHC-P)(1:50-200)
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Cross reactive speciesHuman (Homo sapiens), Mouse (Mus musculus), Rat (Rattus norvegicus)
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Cross Reactive Species detailsNo significant cross reactivity has been observed for this antibody for the tested species. However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species.
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Background informationSenses changes in the extracellular concentration of calcium ions. The activity of this receptor is mediated by a G-protein that activates a phosphatidylinositol-calcium second messenger system.
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Purification methodPurified by Protein A.
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StorageWater buffered solution containing 100ug/ml BSA, 50% glycerol and 0.09% sodium azide. Store at 4°C for 12 months.
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Excitation emission590nm/617nm
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SynonymsCAR; FHH; FIH; HHC; EIG8; HHC1; NSHPT; PCAR1; GPRC2A; HYPOC1; Extracellular calcium-sensing receptor; CaSR; Parathyroid cell calcium-sensing receptor 1
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Also known asCalcium Sensing Receptor Antibody
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Other nameAnti-Calcium Sensing Receptor
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AdvisoryAvoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody, thus reducing its reactivity, specificity and sensitivity. For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube. Prior to use briefly centrifuge the vial to gather all the solution on the bottom.
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PropertiesFor facs or microscopy Alexa 1 conjugate.
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ConjugationAlexa Fluor, ALEXA FLUOR® 594
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ConjugatedAlexa conjugate 1
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DescriptionThis antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided. Antibody for research use. The receptors are ligand binding factors of type 1, 2 or 3 and protein-molecules that receive chemical-signals from outside a cell. When such chemical-signals couple or bind to a receptor, they cause some form of cellular/tissue-response, e.g. a change in the electrical-activity of a cell. In this sense, am olfactory receptor is a protein-molecule that recognizes and responds to endogenous-chemical signals, chemokinesor cytokines e.g. an acetylcholine-receptor recognizes and responds to its endogenous-ligand, acetylcholine. However, sometimes in pharmacology, the term is also used to include other proteins that are drug-targets, such as enzymes, transporters and ion-channels.
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Gene target
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Gene symbolCASR, VN2R1P
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Short nameAnti-Calcium Sensing Receptor
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Techniqueanti-, anti, antibody to, antibodies
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IsotypeImmunoglobulin G (IgG)
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LabelALEXA FLUOR 594
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Alternative nameCalcium Sensing Receptor Antibody, ALEXA FLUOR® 594 Conjugated
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Alternative techniqueantibodies
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Gene info
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Identity
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Gene
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Long gene namecalcium sensing receptor
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Synonyms gene
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Synonyms gene name
- hypocalciuric hypercalcemia 1
- calcium-sensing receptor
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Synonyms
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Synonyms name
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GenBank acession
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Locus
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Discovery year1992-12-04
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Calcium sensing receptors
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VEGA ID
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Locus Specific Databases
Gene info
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Identity
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Gene
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Long gene namevomeronasal 2 receptor 1 pseudogene
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Synonyms gene
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Synonyms gene name
- calcium-sensing receptor like 1
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Synonyms
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GenBank acession
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Locus
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Discovery year2005-05-10
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Entrez gene record
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RefSeq identity
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Classification
- Vomeronasal receptors
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VEGA ID
MeSH Data
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Name
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ConceptScope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
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Tree numbers
- E05.196.401.143
- E05.301.300.096
- E05.478.566.320.200
- E05.601.262
- E05.601.470.320.200
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Qualifiersethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data