Calcium Sensing Receptor (CASR)[Calcium Sensing Receptor]

Products_type

Antibody
Reactivity

Human
Description

The receptors are ligand binding factors of type 1, 2 or 3 and protein-molecules that receive chemical-signals from outside a cell. When such chemical-signals couple or bind to a receptor, they cause some form of cellular/tissue-response, e.g. a change in the electrical-activity of a cell. In this sense, am olfactory receptor is a protein-molecule that recognizes and responds to endogenous-chemical signals, chemokinesor cytokines e.g. an acetylcholine-receptor recognizes and responds to its endogenous-ligand, acetylcholine. However, sometimes in pharmacology, the term is also used to include other proteins that are drug-targets, such as enzymes, transporters and ion-channels.

Identity

HGNC:1514
Gene

CASR
Long gene name

calcium sensing receptor
Synonyms gene
- HHC
- HHC1
Synonyms gene name
- hypocalciuric hypercalcemia 1
- calcium-sensing receptor
Synonyms
- FHH
- NSHPT
- GPRC2A
Synonyms name
- severe neonatal hyperparathyroidism
GenBank acession
- U20760
Locus

3q13.33-q21.1
Discovery year

1992-12-04
Entrez gene record

846
Pubmed identfication
- 7677761
RefSeq identity
- NM_000388
Classification
- Calcium sensing receptors
VEGA ID

OTTHUMG00000159491
Locus Specific Databases
- CASRdb Calcium Sensing Receptor Locus Mutation Database

Name

Models, Chemical
Concept

Scope note: Theoretical representations that simulate the behavior or activity of chemical processes or phenomena; includes the use of mathematical equations, computers, and other electronic equipment.
Tree numbers
- E05.599.495