Activin receptor-like kinase 1 Polyclonal Antibody

• Catalog number
  CAE02090
• Price
  Please ask
• Size
  100 μg

• Other name
  ACVRL1; HHT; ALK1; HHT2; ORW2; SKR3; ALK-1; ACVRLK1; activin A receptor type II-like 1; Activin A receptor, type II-like kinase 1; ALK1; TSR-I; TGF-B superfamily receptor type I; activin A receptor, type II-like kinase 1; serine/threonine-protein kinase r
• Immunogen
  C-KISNSPEKPKVIQ
• Verified reactivity
  Human
• Verified applications
  ELISA, WB
• Raised in
  Goat
• Clonality
  Polyclonal
• Protein number
  Please see Uniprot
• Gene number
  94 (human);
• NCBI number
  NP_000011.2; NP_001070869.1
• Purity
  Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
• Antibody s concentration
  0,5mg/1ml
• Storage recommendation
  Aliquot and store at -20°C. Minimize freezing and thawing.
• Use before
  1 year
• Shipping requirements
  Blue ice
• Estimated production time
  3-7 business days
• Supplementary information
  Expected reactivity based on sequence homology: Human. Please note that this product is not to be confused with the similarly named ALK (anaplastic lymphoma kinase, GeneID 238). Reported variant represent identical protein: NP_000011.2; NP_001070869.1
• Notes
  For research use only. Not for diagnostic procedures.
• Hyperlink
• Properties
  If you buy Antibodies supplied by bioma they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• Group
  Polyclonals and antibodies
• About
  Polyclonals can be used for Western blot, immunohistochemistry on frozen slices or parrafin fixed tissues. The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera.
• Description
  The receptors are ligand binding factors of type 1, 2 or 3 and protein-molecules that receive chemical-signals from outside a cell. When such chemical-signals couple or bind to a receptor, they cause some form of cellular/tissue-response, e.g. a change in the electrical-activity of a cell. In this sense, am olfactory receptor is a protein-molecule that recognizes and responds to endogenous-chemical signals, chemokinesor cytokines e.g. an acetylcholine-receptor recognizes and responds to its endogenous-ligand, acetylcholine. However, sometimes in pharmacology, the term is also used to include other proteins that are drug-targets, such as enzymes, transporters and ion-channels.
• French translation
  anticorps

• Gene target
  Activin   receptor-like   kinase  
• Gene symbol
  ACVRL1, TGFBR1
• Short name
  Activin receptor-like kinase 1 Polyclonal Antibody
• Technique
  Polyclonal, Antibody, antibodies against human proteins, antibodies for, Polyclonal antibodies (pAbs) are mostly rabbit or goat antibodies that are secreted by different B cells, whereas monoclonal antibodies come from a single N cell lineage. Pabs are a collection of immunoglobulin molecules that react against a specific antigen, each identifying a different epitope.
• Label
  Unconjugated
• Alternative name
  Activin receptor-like phosphorylation catalyst 1 polyclonal (antibody to-)
• Alternative technique
  polyclonals, antibodies

Gene info

• Identity
  HGNC:175
• Gene
  ACVRL1
• Long gene name
  activin A receptor like type 1
• Synonyms gene
  • ACVRLK1
  • ORW2
• Synonyms gene name
  • activin A receptor type II-like 1
  • activin A receptor type IL
• Synonyms
  • HHT2
  • ALK1
  • HHT
• Synonyms name
  • activin receptor-like kinase 1
• GenBank acession
  • L17075
• Locus
  12q13.13
• Discovery year
  1994-12-12
• Entrez gene record
  94
• Pubmed identfication
  • 8397373
  • 8640225
  • 22718755
• RefSeq identity
  • NM_000020
• Classification
  • Type 1 receptor serine/threonine kinases
• VEGA ID
  OTTHUMG00000169507
• Locus Specific Databases
  • Hereditary Hemorrhagic Telangiectasia (HHT) Mutation Database
  • LRG_543

Gene info

• Identity
  HGNC:11772
• Gene
  TGFBR1
• Long gene name
  transforming growth factor beta receptor 1
• Synonyms gene
  • MSSE
  • ESS1
• Synonyms gene name
  • multiple self-healing squamous epithelioma
  • transforming growth factor beta receptor I
• Synonyms
  • ALK-5
  • ACVRLK4
  • ALK5
  • TBRI
  • TBR-i
• Synonyms name
  • activin A receptor type II-like kinase, 53kDa
• Locus
  9q22.33
• Discovery year
  1993-09-30
• Entrez gene record
  7046
• Pubmed identfication
  • 1319842
  • 8530052
  • 21358634
• Classification
  • Type 1 receptor serine/threonine kinases
• VEGA ID
  OTTHUMG00000020353
• Locus Specific Databases
  • LOVD - Center for Medical Genetics, Ghent, Belgium

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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