CD18 (human) - Clone MEM-48
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Catalog numberT-1039.0200
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PricePlease ask
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Size200ug
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SynonymIntegrin b2 Subunit
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StorageTemperature+5 ± 3 °C
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HOSTMouse
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CloneMEM-148
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FormatDiluded ascites, Lyophilized
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Species Crossreactivityhuman
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ApplicationIHC, FACS, IP, WB (not reduced)
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ConjugateNA
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Top CategoriesAntibodies
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KeywordsMonoclonal; primary antibody
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Additonal DescriptionMEM-48 recognizes the human ?2 integrin subunit that pairs each of four distinctive CD11 ? subunits to form the CD11/CD18 integrin heterodimers. MEM-48 potently promoted adhesion of LFA-1/K562 transfectants and neutrophils to their respective immobilized ligands, suggesting it to be one of the select class of monoclonal antibodies which can act on the ectodomain of the integrin to induce adhesion. Expression of the epitope recognized by MEM-48 is minimal on ?2 integrin transfectants, T cells, eosinophils, monocytes and neutrophils. Application: IHC (f), FACS, Immunoprecipitation, Western Blot (non-reduced)
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PropertiesHuman proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.
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Gene target
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Gene symbolSNORD115-48, IGLV5-48, IGHV3-48, RNU6-48P, UTP18, HAUS8, ITGB2, SNORD115-45
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Short nameCD18 ( ) - Clone MEM-48
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IsotypeIgG1
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SpeciesHuman, Humans
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Alternative nameCD18 (H. sapiens) - clonality MEM-48
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Clone nameMEM-48
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Gene info
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Identity
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Gene
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Long gene namesmall nucleolar RNA, C/D box 115-48
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Synonyms
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GenBank acession
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Locus
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Discovery year2007-02-16
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Small nucleolar RNAs, C/D box
Gene info
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Identity
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Gene
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Long gene nameimmunoglobulin lambda variable 5-48 (non-functional)
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Synonyms gene name
- immunoglobulin lambda variable 5-48
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GenBank acession
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Locus
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Discovery year2000-05-08
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Entrez gene record
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RefSeq identity
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Classification
- Immunoglobulin lambda locus at 22q11.2
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VEGA ID
Gene info
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Identity
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Gene
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Long gene nameimmunoglobulin heavy variable 3-48
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GenBank acession
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Locus
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Discovery year2000-04-04
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Entrez gene record
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RefSeq identity
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Classification
- Immunoglobulin heavy locus at 14q32.33
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VEGA ID
Gene info
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Identity
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Gene
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Long gene nameRNA, U6 small nuclear 48, pseudogene
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Synonyms gene
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Synonyms gene name
- RNA, U6 small nuclear 48
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Locus
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Discovery year2008-06-10
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Entrez gene record
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RefSeq identity
Gene info
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Identity
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Gene
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Long gene nameUTP18 small subunit processome component
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Synonyms gene
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Synonyms gene name
- WD repeat domain 50
- UTP18 small subunit (SSU) processome component homolog (yeast)
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Synonyms
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GenBank acession
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Locus
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Discovery year2005-02-01
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- UTPb subcomplex
- WD repeat domain containing
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VEGA ID
Gene info
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Identity
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Gene
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Long gene nameHAUS augmin like complex subunit 8
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Synonyms gene
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Synonyms gene name
- HEC1/NDC80 interacting, centrosome associated 1
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Synonyms
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GenBank acession
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Locus
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Discovery year2008-12-16
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- HAUS augmin like complex
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VEGA ID
Gene info
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Identity
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Gene
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Long gene nameintegrin subunit beta 2
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Synonyms gene
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Synonyms gene name
- integrin, beta 2 (antigen CD18 (p95), lymphocyte function-associated antigen 1; macrophage antigen 1 (mac-1) beta subunit)
- integrin, beta 2 (complement component 3 receptor 3 and 4 subunit)
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Synonyms
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Synonyms name
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GenBank acession
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Locus
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Discovery year1986-01-01
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Entrez gene record
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RefSeq identity
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Classification
- Integrin beta subunits
- Complement system regulators and receptors
- CD molecules
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VEGA ID
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Locus Specific Databases
Gene info
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Identity
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Gene
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Long gene namesmall nucleolar RNA, C/D box 115-45
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Synonyms
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Locus
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Discovery year2011-08-22
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Small nucleolar RNAs, C/D box